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Severe alopecia areata greatly impacts quality of life, mental health, and daily activities.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Oral isotretinoin does not cause milia in acne patients.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Physical inactivity is a primary cause of many human illnesses.

Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.

More research is needed to understand how testosterone is maintained in adult males.

The document concludes that autoimmune skin disorders are treated with corticosteroids and immunosuppressive drugs.

PCOS increases sexual pain distress in infertile women.

Hair loss can indicate brain aging and potential small vessel disease, but more research is needed to understand the clinical impact.

Polycystic Ovary Syndrome (PCOS) is common in women with conditions like anovulation, hirsutism, hair loss, and type 2 diabetes, and it can lead to health risks like heart disease, obesity, insulin resistance, and depression. Non-Classic Congenital Adrenal Hyperplasia (NC-CAH) is also discussed.

Taking biotin supplements can cause incorrect thyroid test results, leading to wrong diagnoses.

Isotretinoin effectively reduces acne but causes dry skin, higher skin pH, more redness, and hair loss.

Hormonal changes and conditions like polycystic ovarian syndrome are major causes of adult acne in women, with varying prevalence among different ethnicities.

Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.

People with polycystic ovary syndrome (PCOS) are more likely to have higher levels of depression and anxiety, but their personality traits are similar to those without PCOS.

Melatonin improved mental health and metabolism in women with PCOS.

The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.

Tea, especially green tea, shows promise in cosmetics for skin and hair benefits but more research is needed for effective use.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Quercetin-loaded nanoparticles can penetrate skin, minimize hair loss, and promote hair regrowth, showing slightly better results than a marketed product.

Women with PCOS have more emotional and body image issues than healthy women.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Enzymes play crucial roles in metabolism, health, and disease management.

Essential oils from Curcuma species, like turmeric, have compounds that can fight inflammation, cancer, and bacteria, and can also stimulate hair regrowth in bald males.

5α-Reductase inhibitors may increase depression risk but not dementia or suicide.

Hair analysis can show nutritional status and environmental exposure, with phosphorus being very stable in hair and differences found based on gender and conditions like depression and autism.

Finasteride may cause lasting sexual and mental health issues, and genetic screening could help prevent them.

Latanoprost-loaded nanotransfersomes could help treat hair loss by promoting hair growth.