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In this case study, a girl with hereditary vitamin D resistant rickets had a novel mutation in the VDR gene that affected hair cycling without causing total alopecia, suggesting ligand-independent VDR function in hair cycling.

This review explores how mesenchymal stem cells and their extracellular vesicles may treat various skin diseases by modulating immune responses and promoting healing, though further clinical trials are needed to confirm their safety and efficacy in practice.

This systematic review found that topical minoxidil significantly increases nail growth in healthy individuals and patients with nail disorders, showing a promising mean increase in growth rate and clinical response compared to controls, without serious adverse effects reported.

This study confirms the presence of large structural variations in the genome of Nellore cattle, which may contribute to their environmental adaptation to tropical regions.

This study reports that mesenchymal stromal cell-derived extracellular vesicle injections led to complete hair regrowth in a patient with persistent chemotherapy-induced alopecia.

This study found that conditional deletion of Mof in mice resulted in severe defects in skin development, including compromised epidermal differentiation and hair growth, leading to perinatal lethality.

This study found that morroniside enhanced hair follicle growth and transition through the Wnt/β-catenin signaling pathway in a mouse model, suggesting its potential as a treatment for hair loss.

Liposomes improve minoxidil delivery to hair follicles, enhancing treatment for hair loss.

This study found that near-infrared microscopy can effectively detect complete medulla loss in scalp hair, which may serve as a potential biomarker for breast cancer diagnosis.

In this study, researchers developed an AI-powered platform called VitaDetect, which screens for vitamin deficiencies using image analysis of nails, tongue, and skin, aiming to provide an accessible and early-stage detection tool in resource-limited settings.

This study found that multiphoton microscopy imaging allows for detailed observation and quantitative analysis of collagen alterations in the progression of endometrial cancer, potentially offering a faster, more accurate method for early diagnosis compared to current protocols.

In this study, researchers observed that inhibiting myosin light chain kinase in hair cells reduced stiffness and oscillation in bullfrog hair bundles and increased hearing thresholds in mice.

This study found that CNGC 6, CNGC 9, and CNGC 14 are crucial for maintaining calcium oscillations necessary for normal root hair growth in plants, with mutations leading to defects like swelling and bursting.

In this study, once-daily 5% minoxidil foam and twice-daily 2% minoxidil solution both promoted hair regrowth in women with female pattern hair loss, but noninferiority of the foam was not established.

This review examines hydrogel microneedles for transdermal drug delivery, discussing their applications and challenges but reports no new clinical results.

This study reported that Moracin M, a compound from the Moraceae family, significantly promoted hair growth and vascular regeneration by enhancing cell proliferation and Wnt signaling activation in laboratory settings, suggesting it may offer a promising alternative to existing hair growth treatments like minoxidil.

This upcoming clinical trial at Shenzhen People's Hospital will explore the safety and efficacy of human umbilical cord mesenchymal stem cell-derived small extracellular vesicles as a treatment for androgenetic alopecia in young men, comparing them to minoxidil. Results are not reported yet.

In this in vitro study, niacinamide was found not to stimulate VEGF synthesis across a wide range of doses.

This study found that nestin-expressing hair follicle-derived cells express higher levels of certain neurotrophic factors and neural markers, indicating potential for neuroregenerative therapy applications.

This study found that the combination of TTNPB and CHIR99021 enhanced the derivation of highly advanced neural stem cells from human pluripotent stem cells, with improved chromatin accessibility and neuroectodermal gene expression, and these cells successfully engrafted in rat hippocampi to ameliorate depression-like symptoms.

This study found that human mesenchymal stem cell-derived extracellular vesicles promote the proliferation and migration of hair follicle cells and increase hair shaft elongation in cultured human hair follicles.

This study found that the MsPG3-GFP fusion protein accumulates at the growing root hair tips in Medicago plants, suggesting its role in tip growth during symbiosis.

This study observed that including cationic minoxidil particles in a shampoo facilitated notable hair growth promotion despite a negative surface charge after rinsing, likely due to ionic interactions with the skin.

This study found that patients with the MITF p.E318K variant are more likely to develop multiple primary melanomas and dysplastic nevi with uncommon dermoscopic patterns compared to non-carriers.

This article discusses plasma β-endorphin concentrations during natural and artificially induced winter hair growth in mink but reports no new clinical findings.

This study reported that nonablative monopolar radiofrequency therapy provided sustained reductions in both inflammatory and noninflammatory acne lesion counts and sebum production in participants with moderate-to-severe acne vulgaris, with high patient satisfaction and no significant adverse effects observed up to 12 months posttreatment.

In this study, the researchers reported that minoxidil-loaded transfersomes using a cyclodextrin strategy significantly increased drug stability, skin permeation, and hair regrowth in a mouse model of androgenetic alopecia compared to traditional formulations and commercial tinctures.

This study suggests that mNotch expression plays a significant role in hair follicle differentiation and cell fate selection within the follicle during development.

This study identified a novel missense MAFB variant in a family with some unaffected members, suggesting incomplete penetrance and the potential influence of modifier genes, epigenetic mechanisms, or environmental factors on MCTO phenotype.