research New Intranasal and Injectable Gene Therapy for Healthy Life Extension
Gene therapy in mice increased lifespan and improved health without causing cancer.
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960-990 / 1000+ results research Does Nicastrin Deficiency Cause Melanocytotoxicity in Human Skin as in the Fish Counterpart?
Nicastrin deficiency may cause skin cell damage and pigmentation disorders in humans, similar to effects seen in fish.
research 5-Aminolevulinic Acid Improves Chicken Sperm Motility
5-Aminolevulinic acid can help chicken sperm move better at the right amount.
research Mineral Deficiencies: A Root Cause for Reduced Longevity in Mammals
Not getting enough minerals can lead to health problems and shorter lifespans.
research The Compatibility of Bacillus Thuringiensis Cry Protein-Solubilizing Buffers with the Droplet Feeding Method in Fall Armyworm Larvae
Thymosin beta 4 protects cells from damage by blocking a harmful microRNA and boosting a protective gene.
research Investigation of Antioxidant Activity of Cynanchi Wilfordii Radix and Inhibitory Effect of 5α-Reductase mRNA in Human Dermal Papilla Cells
Cynanchi Wilfordii Radix has strong antioxidant effects and may help treat male hair loss.
research Building a Functional Niche for Hair Follicle Stem Cells
Deleting the CRIF1 gene in mice disrupts skin and hair formation, certain proteins affect hair growth, a new compound may improve skin and hair health, blood cell-derived stem cells can create skin-like structures, and hair follicle stem cells come from embryonic cells needing specific signals for development.
research Targeted Deletion of Crif1 in Mouse Skin Epidermis Impairs Skin Homeostasis
Removing the Crif1 gene in mouse skin disrupts skin balance and hair growth.
research Chapter 14: Low-Level Laser Therapy and Stem Cells
Low-level laser therapy may help stem cells grow and function better, aiding in healing and tissue repair.
research Repurposing a Clinical Antimalarial for the Therapeutic Induction of Lethal ER Stress Targeting BRAF-Kinase Inhibitor-Resistant Malignant Melanoma
Mefloquine, an antimalarial drug, is effective in killing melanoma cells resistant to other treatments by causing lethal stress in the cells.
research MSC-Derived Exosomes Protect Auditory Hair Cells From Neomycin-Induced Damage Via Autophagy Regulation
Exosomes protect ear hair cells from damage by controlling cell waste removal, potentially helping treat hearing loss.
research Proteomic Analysis Identifies Differentially Expressed Proteins Participating in Forming Type III Brush Hair in Yangtze River Delta White Goat
Researchers found four key proteins that affect the development of a specific hair type in Yangtze River Delta white goats.
research The Synergistic Effect of Phototherapy and Active Substances on Hair Growth
Combining light therapy with certain substances improves hair growth in people with hair loss.
research Four Days of Simulated Shift Work Reduces Insulin Sensitivity in Humans
Working night shifts for four days can lower the body's ability to use insulin, which may increase the risk of type 2 diabetes.
research Roles of Type 10 17beta-Hydroxysteroid Dehydrogenase in Intracrinology and Metabolism of Isoleucine and Fatty Acids
This enzyme helps metabolize fatty acids and isoleucine, and could be key in treating neurological diseases and certain cancers.
research Inhibition of 3-Methylcrotonyl-CoA Carboxylase Explains the Increased Excretion of 3-Hydroxyisovaleric Acid in Valproate-Treated Patients
Valproic acid treatment increases a specific acid in urine by blocking an enzyme, possibly causing skin rash and hair loss.
research Polygonum Multiflorum Extract Supports Hair Growth by Elongating Anagen Phase and Abrogating the Effect of Androgen in Cultured Human Dermal Papilla Cells
Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.
research From Structural Resilience to Cell Specification: Intermediate Filaments as Regulators of Cell Fate
Intermediate filaments are crucial for cell differentiation and stem cell function.
research Antidepressant-Like Effect of Fluoxetine May Depend on Translocator Protein Activity and Pretest Session Duration in Forced Swimming Test in Mice
Fluoxetine's effectiveness as an antidepressant in mice depends on a specific protein activity and a 5-minute pretest.
research The Mechanisms and Functions of Interorganelle Interactions
Different parts of cells interact at specific areas to control cell functions like energy production and fat storage.
research Delayed Diagnosis of Kearns-Sayre Syndrome in a 38-Year-Old Male Patient: A Case Report
A 38-year-old man was diagnosed late with Kearns-Sayre syndrome after being wrongly treated for epilepsy.
research Decision Letter: Quantitative Mapping of Human Hair Greying and Reversal in Relation to Life Stress
Hair can naturally regain color, and stress might influence greying and its reversal.
research The Role of Mitochondria in the Non-Targeted Effect of Ionizing Radiation
Mitochondria may influence how cells respond to radiation, affecting nearby non-irradiated cells.
research Anti-Hair Loss Effect of Adenosine Is Exerted by cAMP Mediated Wnt/β-Catenin Pathway Stimulation via Modulation of GSK3β Activity in Cultured Human Dermal Papilla Cells
Adenosine can help treat hair loss by promoting hair growth.
research Cell Fate Decisions: Emerging Roles for Metabolic Signals and Cell Morphology
Metabolic signals and cell shape influence how cells develop and change.
research Neuroendocrinology of the Hair Follicle: Principles and Clinical Perspectives
Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
research A Transition State Analogue of 5′-Methylthioadenosine Phosphorylase Induces Apoptosis in Head and Neck Cancers
MT-DADMe-ImmA can selectively kill head and neck cancer cells without harming normal cells.
research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne
Anti-acne medications may work by reducing the activity of a protein involved in acne development.
research Metformin and Malignant Tumors: Not Over the Hill
Metformin, a diabetes drug, may help prevent and treat various cancers, but more research is needed.
research Anagen Effluvium in Association With Extracorporeal Membrane Oxygenation
A critically ill boy experienced hair loss likely due to the stress of his medical treatments, but his hair regrew completely in 1.5 months.