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In this study, researchers explored the heterogeneity of pigment cells in the human scalp anagen hair follicle bulb and discovered unexpected subpopulations of melanocytes, including immature SOX10-negative cells, highlighting potential non-melanogenic roles or transitional migratory functions that require further investigation.

This study found that pimecrolimus enhances melanin synthesis and promotes melanocyte migration, possibly by increasing MITF protein expression, which may explain its effectiveness in repigmenting vitiligo.

This study found that CK15 is an unreliable marker for assessing bulge zone integrity in cicatricial alopecia follicles due to its altered expression in diseased conditions.

This study suggests that down-regulation of vasculature-related genes in dermal papilla cells from balding scalps might contribute to the development of androgenetic alopecia.

Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.

In this study, the expression of Gnαs was significantly higher in black mice compared to white mice, suggesting its potential involvement in coat color formation in mice.

This study observed that vimentin and transthyretin proteins were more highly expressed in black sheep skins compared to white, suggesting their involvement in coat color formation.

This study suggests that chronic stress can lead to decreased skin pigmentation in mice by disrupting the skin's HPA axis, potentially making stress a risk factor for depigmentation.

This study found that induced expression of mir-302 can reprogram human hair follicle cells into induced pluripotent stem cells through a novel epigenetic mechanism involving global demethylation.

This study demonstrated that troxerutin may protect human dermal papilla cells from H2O2-induced damage and suggests potential in treating alopecia by inhibiting ROS-mediated cellular damage.

This study observed that the genes WNT7A, CASP7, and TNF were overexpressed in early stages of androgenetic alopecia, suggesting involvement of the WNT pathway, apoptosis, and inflammation in the disorder's development.

In this study, rice bran mineral extract increased expression of anagen-related proteins and decreased inflammatory markers in human dermal papilla cells, suggesting potential for hair growth enhancement and prevention of hair loss.

This study found that miRNA-24 downregulates the KLF6 gene, influencing coat color by affecting melanogenesis pathways in Cashmere goats, and that miRNA-24 inhibition increased melanin content in mice.

This study found that arctiin, a compound from Arctium lappa, demonstrated protective effects against oxidative stress-induced dysfunction in human hair dermal papilla cells, suggesting potential therapeutic use for alopecia.

Fibroblasts can be turned into melanocytes for potential skin treatments.

This study reports that the side population technique can isolate melanocyte stem cells from human hair follicles, potentially allowing them to be used for skin pigmentation repopulation.

This study demonstrates that extracellular ATP induced by UV radiation promotes melanin production in human melanocytes, suggesting ATP-induced purinergic signaling may influence skin pigmentation.

Hair graying is caused by the loss of pigment cells due to poor maintenance of stem cells in the hair follicle.

This review explores recent findings on the roles of melanocyte and melanocyte stem cells in the hair follicle, highlighting their importance for skin health and potential applications in regenerative medicine, but reports no new clinical results.

This review discusses the interactions between melanocyte stem cells and their niche in hair regeneration and repair, but reports no new results; recent studies on molecular pathways are highlighted.

This review discusses melanocytes' role in pigmentation, their clinical significance in conditions like vitiligo and hair graying, and highlights current research on hair follicle regeneration without reporting new clinical results.

This article discusses melanocyte development from neural crest cells and reports no new experimental results; the authors suggest a broader range of functions for melanocytes than previously recognized.

In this study, Epimedii Folium extract was found to enhance melanin production and promote pigmentation through mechanisms involving the MAPK/ERK1/2 pathway in both in vitro and in vivo models.

This study developed molecular signatures for dermal papilla cells and their niche, uncovering novel signaling regulators and genes linked to hair disorders, which may inform future hair development research.

This review discusses the roles and mechanisms of chromatin remodelers and their subunits in mammalian development, but reports no new experimental results.

This article discusses the role of human hair follicles in neuroendocrinology and suggests potential new therapeutic targets by examining how neuromediators influence hair growth, pigmentation, and stem cell biology in organ cultures.

This study found that PPAR alpha, -delta, and -gamma are expressed in human hair follicle cells, and clofibrate exhibited a beneficial effect on hair follicle survival in culture within a specific concentration range.

Runx1 is crucial for proper hair structure and development.

This review summarizes the current understanding of microRNAs in skin biology, highlighting their roles in processes like wound-healing and aging, without presenting any new experimental results.

This study generated a Dct-H2BGFP mouse model that allows for effective identification and isolation of melanocytic cells in vivo, facilitating research into their molecular and biological properties.