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Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Neurosteroids show promise for treating epilepsy and more research is needed.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.

People with polycystic ovary syndrome have a higher chance of having chronic thyroiditis.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.

Blocking CRF-R1 can reduce alcohol intake in stressed mice.

Adrenal disorders can cause lasting brain and behavior issues in children.

The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.

Hormone treatments can help with women's skin and hair disorders, but they need careful monitoring and more research.

Hair loss linked to metabolic issues and insulin resistance; early assessment may reduce future health risks.