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A weight loss program with a special fast helped patients lose an average of 41-47 pounds and improved their health, but maintaining the weight loss was challenging.

Procyanidin compounds from grape seeds were found to significantly increase mouse hair growth.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Biotin supplements may improve hair and nail growth in people with certain deficiencies or conditions, but there's not enough evidence to recommend it for healthy individuals.

Acne treatment varies, with topical and systemic therapies effective, and more research needed on treatment order and long-term effects.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Spironolactone effectively reduces hair growth in women with hirsutism and is generally well-tolerated.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

New treatments for male hypogonadism are effective and should be personalized.

Testosterone with or without finasteride doesn't improve thinking skills in older men with low testosterone.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

TPA is about 50 times more effective at promoting tumors than MZ.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Chemotherapy often causes skin, nail, and hair side effects, significantly impacting quality of life.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Imiquimod 5% cream reduced equine sarcoids in most cases.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Sphynx cats are hairless and Devon Rex cats have curly hair due to specific genetic mutations.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.

Four genetic risk spots found for hair loss, with WNT signaling involved and a link to curly hair.

Minoxidil and finasteride are effective for male hair loss, minoxidil for female hair loss, and various treatments like corticosteroids work for alopecia areata; treatment should be tailored to the individual.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.