Efficacy of Imiquimod 5% Cream in the Treatment of Equine Sarcoids: A Pilot Study

    July 2006 in “ Veterinary Dermatology
    Sandra A. F. Nogueira, Sheila M. F. Torres, Erin Malone, Sandra F. Diaz, Carl R. Jessen, Sophie Gilbert
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    Studysummary In this pilot study, the researchers found that topical application of imiquimod 5% cream may significantly reduce equine sarcoid tumor size, with 80% of tumors showing more than 75% reduction.
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    This pilot study evaluated the efficacy of imiquimod 5% cream as a topical treatment for equine sarcoids in 15 horses with 19 tumours. The treatment was applied three times a week for up to 32 weeks. Of the 15 tumours that completed the study, 80% showed more than a 75% reduction in size, and 60% completely resolved within 8 to 32 weeks. Adverse effects were generally limited to the tumour and adjacent areas. The study suggested that imiquimod could be a therapeutic option for equine sarcoids, but further research was needed to confirm these findings.
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