9 citations
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February 2024 in “Indian Dermatology Online Journal” This study discusses the potential of advanced imaging technologies in dermatology to improve diagnostic accuracy and reduce the need for invasive procedures like biopsies, while noting significant barriers in adoption and accessibility in India due to costs and infrastructure constraints.
7 citations
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May 1988 in “International Journal of Dermatology” This case report describes an 18-year-old man with pili annulati, characterized by a "shagreened" appearance of the hair shaft with alternate bright and dark bands and wide holes throughout the cortex.
2 citations
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November 2023 in “Skin Research and Technology” This study found that RCM combined with dermoscopy can differentiate disease states between alopecia areata, tinea capitis, nevus sebaceous, and linear scleroderma of the scalp by identifying distinct dermal and follicular patterns.
July 2026 in “Diagnostics” This review outlines the key principles and clinical applications of multimodal non-invasive skin imaging technologies, emphasizing their combined strengths in enhancing diagnosis and treatment assessment in dermatology.
January 2026 in “Journal of Cosmetic Dermatology” This study observed that repeated low-depth microneedling in patients with androgenetic alopecia led to initial hair improvement but subsequently caused hair-shaft fragility and breakage, suggesting iatrogenic damage.
December 2025 in “Journal of Mycology and Infection” In this case report, a 2-month-old girl with tinea capitis showed significant improvement after treatment with oral griseofulvin and topical ketoconazole. The study emphasizes the importance of layered diagnostics and systemic therapy for effective management of this fungal scalp infection in infants.
April 2022 in “Australasian Journal of Dermatology” This case report describes a rare presentation of recurrent plaque psoriasis on the penile shaft, which was controlled with systemic therapy after topical treatments failed.
February 1999 in “The anatomical record” This study observed defects in hair cuticle cross-linking in some, but not all, mouse mutants with sparse or structurally unsound hair.
140 citations
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December 1998 in “Journal of Investigative Dermatology” Apoptosis in hair follicles varies by growth phase, with TGF-β possibly starting the catagen phase.
6 citations
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May 2022 in “Pharmaceutics” This study demonstrates that MPM-FLIM multimodal imaging can effectively assess the delivery and dissolution of zinc pyrithione particles in human skin follicles using different application techniques.
29 citations
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January 2019 in “Journal of the European Academy of Dermatology and Venereology” This study found that trichoscopic examination is useful for diagnosing and monitoring systemic lupus erythematosus, with severe diffuse non-scarring alopecia indicating active disease.
15 citations
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August 2020 in “Analytical chemistry” This study observed that lipids in human hair accumulate in specific areas and do not significantly impact water permeability, highlighting the utility of AFMIR for studying complex biomaterials.
14 citations
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January 2020 in “International Journal of Biological Sciences” This study explored the use of multiphoton microscopy to monitor changes in tumors and surrounding tissues in breast cancer patients undergoing neoadjuvant chemotherapy, finding it may effectively detect treatment response at cellular levels without using exogenous contrast agents.
8 citations
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January 2020 in “PeerJ” This study found significant structural and compositional differences in hair affected by alopecia areata compared to healthy hair, using a range of physico-chemical investigation methods.
This review discusses recent advances in noninvasive hair imaging technologies, such as global photography, trichoscopy, reflectance confocal microscopy, and optical coherence tomography, highlighting their potential to improve hair diagnostics and treatment monitoring, while also outlining their clinical applications and limitations.
April 2016 in “Journal of The American Academy of Dermatology” This study suggests that while low-cost USB microscopes can correctly identify certain hair shaft features, their ability to detect other crucial trichoscopic features is limited, indicating they are not reliable for routine scalp assessments without further trials.
1 citations
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January 2022 in “Brazilian Journal of Pharmaceutical Sciences” This study investigated the physicochemical properties of polystyrene-b-poly(acrylic acid) nanovesicles coated with modified chitosans, finding that they can effectively control surface charge and potentially serve as drug delivery carriers with a 50.7% encapsulation efficiency for minoxidil.
July 2026 in “Preprints.org” In this study, incorporating a novel amino acid compound into a hair-straightening formulation improved humidity-resistant straightening and enhanced the surface and mechanical properties of hair fibers, including increased bending stiffness, reduced friction, and better shape retention under high temperature and humidity conditions.
Detailed history and physical examination are crucial for diagnosing hair loss.
25 citations
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February 2007 in “Forensic science international” This study found that different decontamination protocols caused varying levels of cuticle damage in hair, with aqueous buffer treatment resulting in the most substantial degradation.
86 citations
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August 2014 in “Journal of The American Academy of Dermatology” This article discusses the history taking and clinical examination process for diagnosing alopecia and outlines a diagnostic approach, noting that it reports no new clinical results.
1 citations
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January 2024 in “Annals of Dermatology” This study suggests that analyzing microscopic hair morphology, particularly loss of typical clubbing and proximal tapering, may help predict the clinical course of alopecia areata.
122 citations
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April 1995 in “Journal of Cutaneous Pathology” The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.
12 citations
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August 2013 in “Facial Plastic Surgery Clinics of North America” This article reviews the essential aspects of patient consultation and examination in hair restoration surgery and outlines factors affecting candidate selection and contraindications, but reports no new clinical results.
2 citations
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January 2025 in “Dermatology Practical & Conceptual” In this study, dermoscopic examination of COVID-19 patients revealed significant microvascular changes in the proximal nailfold, such as avascular areas and disorganized capillary architecture, compared to healthy controls, with some regression of these changes observed over time.
May 2025 in “International Journal For Multidisciplinary Research” In this study, veterinary examinations of 150 domestic canines and felines revealed that M. canis was the predominant dermatophyte, affecting 9 cats and 9 dogs, with dogs showing more severe lesions and higher neutrophil counts in the cytological analysis.
July 2021 in “Australasian Journal of Dermatology” This manuscript describes a proposed ‘trichoscopy-assisted hair pull test’ that enhances the diagnosis of hair loss conditions by allowing immediate examination of proximal hair shafts and roots in patients with a positive hair pull test.
37 citations
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July 2005 in “Journal of The American Academy of Dermatology” This article reviews the clinicopathologic features of short anagen syndrome in a child and suggests diagnostic methods like clinical examination and scalp hair growth rate measurement, without reporting new clinical results.
November 2020 in “Skin Research and Technology” This study found that videodermoscopy showed higher sensitivity and specificity than clinical examination for diagnosing female pattern hair loss and may serve as an alternative to scalp biopsy in the future.
1 citations
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July 2022 in “Case reports in endocrinology” This case report concludes that a combination of physical examination, hormonal evaluation, and imaging studies is crucial for identifying malignant adrenal masses, with radical excision and adjuvant therapy improving patient outcomes.