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This article reviews the applications of microneedle technology in drug delivery, dermatology, and cosmetics, but it presents no new experimental or clinical findings.

This study found that the film-trigger applicator system enhanced drug delivery efficiency and skin penetration of dissolving microneedles compared to traditional patch systems in both lab and animal models.

This systematic review examines the landscape of cosmetic microneedling using SWOT analysis, identifying strengths like precise delivery and self-administration, while noting challenges such as potential skin damage and regulatory issues, with opportunities in AI-enhanced targeted treatments noted by these researchers.

This study found that using a standardized protocol with microspheres of approximately 1.5 micrometers enhances penetration into hair follicles, particularly when skin is treated with cyanoacrylate skin surface stripping.

This study found that finite element analysis-guided design improved bubble microneedles' controlled tip separation and insertion strength, supporting effective transdermal and sublingual drug delivery.

This review discusses the current state and potential future of polymer-based microneedles for transdermal drug delivery, without reporting new empirical results; it highlights their applications and existing challenges.

This study developed a co-design framework using finite element analysis to optimize bubble microneedles, achieving controlled tip separation and effective drug delivery through the skin and mucosa while maintaining insertion strength.

This review highlights that microneedling is an effective and flexible technique for enhancing transdermal drug delivery, with numerous applications in both cosmetic and therapeutic dermatological treatments. The researchers note that further advancements are likely to increase its efficacy and safety.

This review highlights the application of microneedle technology as a promising advancement in psoriasis management, focusing on its roles in enhanced transdermal drug delivery and minimally invasive biomarker monitoring, while also discussing current challenges and future research directions.

This study found that administering botulinum toxin A via Flex-PADs to mouse footpads inhibited sweating similarly to traditional injections, suggesting a promising patient-friendly delivery method for hyperhidrosis treatment.

This review discusses various microneedle technologies for long-acting drug delivery, highlighting design considerations and challenges in bringing these minimally invasive devices to market, but it reports no new clinical results.

This review highlights the use of microneedling devices and patches to deliver cosmetic agents through the skin, noting their applications in skin rejuvenation and safety considerations such as potential skin irritation and infection.

This study introduces a co-design framework using finite element analysis to optimize separable bubble microneedles, demonstrating enhanced transdermal and sublingual drug delivery in preclinical models. In vivo results showed faster hair regrowth and glucose lowering in animals, indicating potential improvements over traditional methods.

This review explores the potential, challenges, and recent advancements of dissolving microneedles in drug delivery, summarizing their varied applications and current limitations without providing new clinical results.

In this study, researchers developed microparticle-embedded gas-propelled microneedles that showed higher drug loading and transdermal delivery efficiency compared to traditional microneedles.

This study proposes a metal-organic gel-encapsulated microneedle system with antibacterial, anti-inflammatory, and pro-angiogenic properties for treating infected wounds, demonstrating potential for precise and adaptive management by targeting various stages of wound healing.

This study developed a personalized microneedle that delivers finasteride directly to the skin, facilitating a sustained release and potentially reducing side effects associated with oral administration.

This review examines the use of microneedles for treating alopecia areata, highlighting their ability to enhance drug delivery through the skin by bypassing the outer barrier and promoting hair growth with minimal invasiveness.

This study found that a ceria nanozyme-integrated microneedles patch accelerated hair regeneration in an androgenetic alopecia mouse model more effectively than minoxidil, with reduced application frequency and minimal skin damage.

This review discusses the safety concerns associated with new treatments for non-scarring alopecias, highlighting that while these therapies such as JAK inhibitors and oral minoxidil show efficacy in hair regrowth, their safety profiles vary significantly, requiring careful consideration of benefits and risks.

This abstract discusses platelet-rich plasma therapy for patterned hair loss but provides no new clinical results, suggesting further research is needed to determine its effectiveness.

This review article highlights that mesotherapy, a popular non-surgical procedure in aesthetic dermatology, involves injecting a mixture of compounds into the skin for purposes like skin rejuvenation and hair loss treatment, but lacks large-scale studies on its efficacy and safety.

This study suggests that combination therapies including minoxidil with either finasteride, low-level laser light therapy, or microneedling are more effective than minoxidil alone for treating androgenetic alopecia.

Results are not reported in this letter to the editor on the use of scalp threading with polydioxanone monofilament threads for hair restoration.

In this study, microneedling with a depth of 0.6 mm, alongside minoxidil, significantly improved hair count and thickness in patients with androgenetic alopecia compared to minoxidil alone, and was more beneficial than a 1.2 mm depth.

This protocol outlines a study aiming to determine if combining 660 nm red laser photobiomodulation and microneedling increases hair density in female pattern hair loss, but it reports no results yet.

This review explores the potential of microneedling as a drug delivery system for treating melasma, focusing on its mechanisms, safety, efficacy, and clinical advantages over conventional therapies like hydroquinone and lasers.