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The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Zinc is effective for treating various skin conditions, including warts and acne.

Accurate diagnosis and effective oral treatment are key to managing tinea capitis and preventing its spread.

Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.

No single treatment is consistently effective for alopecia areata, and more research is needed.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.

Ethosomes improve finasteride delivery through skin for hair loss treatment.

Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.

Nanocrystals improve skin penetration and stability of caffeine, suggesting a new method for delivering similar substances through the skin.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

The cosmetic industry should adapt to the varied beauty standards of ethnic groups and offer specialized treatments.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.

Nanoparticles improve minoxidil skin permeation, but more research needed for effective hair growth.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

Doctors should know how to diagnose and treat PCOS, which often involves checking for high male hormone levels and using medications to manage symptoms.