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This review highlights that microneedling is an effective and flexible technique for enhancing transdermal drug delivery, with numerous applications in both cosmetic and therapeutic dermatological treatments. The researchers note that further advancements are likely to increase its efficacy and safety.

This review summarizes the role of miRNAs in epidermal and hair follicle development, highlighting their potential impact on understanding gene regulatory networks and applications in disease treatment and molecular breeding.

This article describes the Dermatologic Surgery journal, which publishes comprehensive, peer-reviewed information on cosmetic and reconstructive skin surgery, but offers no new research findings.

This study found that melatonin implants in cashmere goats significantly altered the expression pattern and co-expression of miRNAs, suggesting a possible role in inducing a second growth of cashmere.

This study found that 5alpha-reductase type 1 localizes specifically to sebaceous glands in both normal and acne follicles, suggesting its role in sebum regulation.

This study reviewed 55 studies to assess the bacterial microbiome in hair follicles across different inflammatory skin and hair conditions, reporting shifts in the abundance of Cutibacterium and Staphylococcus among various diseases, though the causal significance remains unclear.

This study highlights that Demodex mites, commonly found on human skin, can cause significant eye and skin issues such as blepharitis, rosacea, and dermatitis when present in abnormally high densities, underscoring the need for targeted management strategies.

This study suggests that MUC1 expression is significantly higher in follicular mucinoses compared to other dermal mucinoses, particularly in lymphoma-associated forms, indicating its potential as a target for immunotherapy.

This study developed a genetic toolbox to engineer Cutibacterium acnes for dermal applications, successfully creating a strain that secretes antioxidants to reduce oxidative stress in a UV stress model.

This study suggests that the expression patterns of keratin and filaggrin indicate milia may originate from the outermost cells of the hair bulge in the outer root sheath.

The researchers developed semi-dissolving microneedle patches using TEMPO-oxidized bacterial cellulose nanofibers, which allow effective transdermal drug delivery by forming micro-channels for large drug quantities, overcoming traditional microneedles' low drug loading.

This study found that Demodex folliculorum and Demodex brevis mites can cause eyelid follicular and glandular changes, potentially contributing to ocular disease in humans.

This study found that disruptions in the skin microbiome, known as dysbiosis, play a significant role in various skin conditions, including atopic dermatitis, psoriasis, acne, rosacea, skin cancer, and impaired wound healing, by altering immune responses and barrier functions.

This article discusses a combination of photobiomodulation and microneedling as a four-week treatment for male androgenetic alopecia in a case series, but reports no new clinical results.

This study found that mimosine dipeptide enantiomers inhibit melanogenesis and cyclooxygenase enzymes in B16F10 melanoma cells, suggesting potential for treating skin hyperpigmentation and inflammation.

This study introduced a surgical technique involving tweezers to effectively treat acne vulgaris, achieving complete healing in 99% of 4566 patients within up to 50 treatments, potentially reducing psychological distress and medication side effects.

This study on androgenetic alopecia in mice introduced a novel therapy combining microneedle patches and cold atmospheric plasma to enhance minoxidil delivery, leading to improved hair regeneration by boosting vascular growth and reshaping the hair follicle microenvironment.

This study found that combining microdermabrasion, a topical regimen, and low-fluence QS Nd:YAG laser treatment effectively cleared melasma in women, with 81% of participants achieving over 75% clearance and minimal side effects.

This review explores the mechanisms, techniques, and clinical applications of microneedling, highlighting its advantages and challenges in skin rejuvenation, and discusses future innovations in the field as it continues to evolve.

In this study, miR-31 was found to play a significant role in hair cycle regulation in mice by controlling key gene expressions involved in hair growth and differentiation.

This study found that overexpression of miR-214 in keratinocytes inhibits hair follicle development and cycling by targeting β-catenin in the Wnt signaling pathway.

This report details a rare case of late-onset, bilateral nevus comedonicus on the eyelids in a 79-year-old man, discussing its clinical presentation and histopathologic features without presenting new research findings.

This study observed that pancreatic cancer-related skin lesions in mice are linked to microbiota imbalances, specifically noting changes in the abundance of certain bacterial genera, which may offer potential diagnostic or therapeutic targets for managing skin complications in humans with pancreatic cancer.

This review discusses the use of microemulsions for transdermal drug delivery and emphasizes the importance of component selection for enhancing drug permeation and skin tolerance, without reporting new clinical results.

This review discusses the use of microneedling with a dermaroller for treating acne scars, hair loss, and wrinkles, and reports no new clinical results.

This case study describes a pregnant woman who developed a pruritic rash with follicular lesions containing yeast-like organisms, resistant to conventional acne treatments.

This study found that the new delivery system HL@Mi enhanced the skin penetration, local bioavailability, and safety of minoxidil, supporting improved hair growth in an androgenetic alopecia animal model.

This study found that the skin microbiome in patients with hidradenitis suppurativa differs significantly from healthy controls, suggesting a potential link between microbial imbalance and the disease.

This paper reviews the use of microneedling alone and in combination with platelet-rich plasma for various skin conditions, but it reports no new clinical findings.

This review discusses the potential of gut microbiota-derived exosomes as drug delivery systems and reports no new clinical results; the authors highlight their promise for precision medicine.