research Alefacept for Alopecia Areata
Alefacept showed some effectiveness for alopecia areata but needs more research.
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research New Onset of Alopecia Areata in a Patient with SARS-CoV-2 Infection: Possible Pathogenetic Correlations
COVID-19 infection may trigger alopecia areata in some patients.
research The Role of Vitamin D in Non-Scarring Alopecia
Low vitamin D might be linked to certain types of hair loss, and supplements could help, but more research is needed.
research FOXN1 Deficient Nude Severe Combined Immunodeficiency
FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.
research The Hair Follicle: An Underutilized Source of Cells and Materials for Regenerative Medicine
Hair follicles are valuable for regenerative medicine and wound healing.
research Exploring the Brain-Skin Connection: Leads and Lessons from the Hair Follicle
Hair follicles on the scalp interact with and respond to the nervous system, influencing their own behavior and growth.
research Melanocyte and Gonad Activity as Potential Severity Modifying Factors in C3H/HeJ Mouse Alopecia Areata
Gonadal hormones significantly affect the severity of alopecia areata in mice.
research The Basic Science of Hair Biology
Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.
research Whole-Genome Bisulfite Sequencing of Goat Skins Identifies Signatures Associated with Hair Cycling
DNA methylation changes are linked to hair growth cycles in goats.
research Immune Cell Regulation of the Hair Cycle
Immune cells affect hair growth and could lead to new hair loss treatments.
research iNKT Cells Ameliorate Human Autoimmunity: Lessons from Alopecia Areata
iNKT cells can help prevent and treat alopecia areata by promoting hair regrowth.
research Study of Gene Expression Alteration in Male Androgenetic Alopecia: Evidence of Predominant Molecular Signaling Pathways
Hair loss involves immune responses, inflammation, and disrupted signaling pathways.
research Insulin-Like Growth Factor-1: Roles in Androgenetic Alopecia
IGF-1 affects hair loss and could be a potential treatment.
research Biochemistry of Epidermal Stem Cells
The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
research Thyroid Diseases and Skin Autoimmunity
Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.
research Efficacy of Korean Red Ginseng in the Treatment of Alopecia Areata
Korean Red Ginseng may help improve hair regrowth when used with corticosteroid injections for Alopecia Areata.
research Human Gene Correlation Analysis: A Tool for the Identification of Transcriptionally Co-Expressed Genes
The HGCA tool helps identify genes that work together by analyzing their co-expression patterns.
research Immunology of Alopecia Areata
Alopecia areata, a type of hair loss, is likely an autoimmune disease with a genetic link, but its exact cause is still unknown.
research Group IID, IIE, IIF, and III Secreted Phospholipase A2s
Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
research Recombinant Human Hepatitis B Vaccine Initiating Alopecia Areata: Testing the Hypothesis Using the C3H/HeJ Mouse Model
The hepatitis B vaccine did not cause hair loss in the tested mice.
research Physical Methods for Topical Skin Drug Delivery: Concepts and Applications
New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.
research Adrenal 21-Hydroxylase Gene Mutations in Slovenian Hyperandrogenic Women: Evaluation of Corticotrophin Stimulation and HLA Polymorphisms in Screening for Carrier Status
The study concluded that testing hormone levels after stimulation is not reliable for identifying carriers of 21-hydroxylase deficiency; genetic testing is necessary.
research Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells
A specific DNA region is crucial for Foxn1 gene expression in thymus cells but not in hair follicles.
research Effects of Mesenchymal Stem Cell Therapy on Alopecia Areata in Cellular and Hair Follicle Organ Culture Models
Mesenchymal stem cell therapy may help treat alopecia areata by promoting hair growth and reducing inflammation.
research A Comparative Analysis of Immune Privilege in Pregnancy and Cancer in the Context of Checkpoint Blockade Immunotherapy
The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.
research The Changing Landscape of Alopecia Areata: The Translational Landscape
New treatments for hair loss are showing promise due to better understanding of genetics and the immune system.
research Hair Follicles and Their Role in Skin Health
Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
research The Genetics of Alopecia Areata
Alopecia areata has a complex genetic basis that was not fully understood as of 2001.
research The Promise and Challenges of Cell Therapy for Psoriasis
Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.
research Immunopathology of the Human Hair Follicle
The document concludes that immune system abnormalities cause alopecia areata, but the exact process is still not completely understood.