![Benzo[c]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1](/images/research/ff6e6cbe-cb9c-4d11-87ef-671d28ffd4fa/small/15506.jpg)
research Benzo[c]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1
Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.
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research Lessons Learned from the First Decade of Laser-Assisted Drug Delivery
Laser-assisted drug delivery has shown improved treatment outcomes for skin conditions and has potential to reduce side effects and treatment time.
research Histochemical Observation of the Cell Membrane Complex of Hair
The Cell Membrane Complex in hair has both water-attracting and water-repelling layers.
research Finasteride Topical Delivery Systems for Androgenetic Alopecia
Topical finasteride can effectively treat male pattern baldness with fewer side effects than oral use.
research Treatment-Resistant Giant Unilateral Bowen’s Disease of the Scalp Responding to Radiotherapy
Radiotherapy was effective for treating a large scalp plaque of Bowen's disease when other treatments failed.
research Low-Level Light-Assisted Photodynamic Therapy Using a Wearable Cap-Like Device for the Treatment of Actinic Keratosis of the Scalp
A wearable cap-like device using light therapy reduced scalp skin lesions by 71% and was painless.
research Synthesis and Structure–Activity Investigation of Iodinated Arylhydantoins and Arylthiohydantoins for Development as Androgen Receptor Radioligands
Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.
research A Cell Membrane-Level Approach to Cicatricial Alopecia Management: Is Caveolin-1 a Viable Therapeutic Target in Frontal Fibrosing Alopecia?
Targeting the protein Caveolin-1 might help treat a type of scarring hair loss called Frontal Fibrosing Alopecia.
research Formulation and Evaluation of Herbal Hair Gel Containing Fenugreek Seed Extract for Nourishment and Hair Growth
Herbal hair gel with fenugreek seed extract was found to increase hair growth.
research A Novel In Vivo Active Pemphigus Model Targeting Desmoglein 1 and Desmoglein 3: A Tool Representing All Pemphigus Variants
New mouse models of Pemphigus show severe symptoms and need better treatments.
research Preparation and Evaluation of Herbal Gel Containing Fenugreek Seed Extract for Hair Growth
The fenugreek seed extract gel can help with hair growth and reduce hair problems.
research Interactions Between Damaged Hair Keratin and Juglone as a Possible Restoring Agent: A Vibrational and Scanning Electron Microscopy Study
Juglone from walnut extracts may help repair damaged hair.
research Effect of Hydroxypropyl Methylcellulose in Release Profile of Air Fresheners Gel Using Carrageenan and HPMC
The F2 Emulgel with Tridax procumbens extract showed good physical properties and antimicrobial effectiveness for wound healing.
research Formulation and Evaluation of Emulgel Containing Tridax Procumbens Extract
The F2 Emulgel with Tridax procumbens extract showed the best qualities for healing wounds.
research Hepatitis Lupus in Systemic Lupus Erythematosus in Male Patients
Lupus hepatitis can affect male SLE patients and is treatable with specific medications.
research Formulation of Hair Tonic with Aloe Vera Extract and Hair Growth Activity Test on Male White Rats
Aloe vera hair tonic with 10% and 15% concentrations effectively promoted hair growth in male rats.
research Anti-Aging Medicine for Hair
Early anti-aging hair treatments should focus on anti-inflammatory agents and promoting healthy hair growth cycles.
research Woman with Rhupus Syndrome: Systemic Lupus Erythematosus and Rheumatoid Arthritis
A 29-year-old woman with symptoms of both lupus and rheumatoid arthritis improved with specific medications.
research A Prospective Study of Daylight Photodynamic Therapy for Treatment of Actinic Keratoses in an Irish Population
Daylight photodynamic therapy is effective and well-tolerated for treating actinic keratoses with minimal side effects.
research Unveiling the Potential of Sansevieria Trifasciata Prain Fraction for the Treatment of Androgenetic Alopecia by Inhibiting Androgen Receptors Based on LC-MS/MS Analysis and In-Silico Studies
Sansevieria trifasciata Prain shows promise for treating hair loss by inhibiting androgen receptors.
research Nonsteroidal Inhibitors of Human Type I Steroid 5α-Reductase
New compounds called benzoquinolinones may treat conditions linked to excess DHT.
research Transport of Biotin in Human Keratinocytes
Human skin cells have a high-affinity system for biotin transport, crucial for skin health.
research Characterization of the Lipid Composition at the Proximal Root Regions of Human Hair
Human hair contains various lipids that vary among individuals and help protect the hair.
research Integral Hair Lipid in Human Hair Follicle
Human hair has a protective lipid layer that can be damaged by moisture and treatments, affecting hair growth and health.
research Antiandrogens and the Skin
Antiandrogens can treat acne, hirsutism, and seborrhea by reducing sebum production and androgen action.
research Structure-Guided Manipulation of the Regioselectivity of the Cyclosporine A Hydroxylase CYP-sb21 from Sebekia Benihana
Scientists improved an enzyme to better produce a hair growth-promoting chemical from an immunosuppressant.
research Abstracts
Mice treatments didn't grow hair, a patient treatment may affect immune response, and people with hair loss often feel anxious or depressed.
research Inactivation of Autophagy Leads to Changes in Sebaceous Gland Morphology and Function
Autophagy is crucial for normal sebaceous gland function and sebum composition.
research Follicular-Targeted Delivery of Spironolactone Provided by Polymeric Nanoparticles
Nanoparticles can effectively deliver spironolactone to hair follicles for treating alopecia and acne.
research In Vivo Evaluation of Eclipta Alba Extract as Anticancer and Multidrug Resistance Reversal Agent
Eclipta alba extract may work as an anticancer agent and help reverse drug resistance.