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Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Dermatoscopy is a useful tool for diagnosing hair disorders and can help choose samples for more detailed analysis.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Hair usually grows back 1-3 months after treatment for anagen effluvium, and children with Loose Anagen Hair Syndrome often improve by adolescence.

Most patients with chronic kidney disease have skin problems, which get worse as the disease progresses, and dialysis doesn't greatly reduce these issues.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

Disruptions in hair follicle fibroblast dynamics can cause hair growth problems.

Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.

K16 can partially replace K14 but causes hair loss and skin issues.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.

Certain microRNAs in the fluid around eggs are linked to Polycystic Ovary Syndrome and may help diagnose it.

Diane 35 plus finasteride is more effective in reducing hair growth and androgen levels, but may decrease libido.

Shift nurses show altered body temperature and stress hormone levels, suggesting their body clocks adjust to irregular schedules.

A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.

People with polycystic ovary syndrome may have a higher risk of heart problems due to abnormal nervous system control of their heart and blood pressure.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Using patients' own fat-derived cells to treat alopecia areata significantly improved hair growth and was safe.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

Quercetin may help with PCOS symptoms, but more research is needed.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.