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Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Lichen planus pigmentosus causes dark skin patches and is treated by avoiding triggers and using anti-inflammatory medications.

Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.

All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.

Polygonum multiflorum extract helps grow hair by activating certain hair growth signals in mice.

Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.

Cancer patients treated with immune checkpoint inhibitors may develop alopecia, but some hair regrowth is possible with treatment.

Antioxidants can benefit skin health but should be used carefully to avoid negative effects.

Alopecia Areata is an autoimmune condition often starting before age 20, with varied treatment success and a need for personalized treatment plans.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Treatments for melanin disorders exist, but more effective options needed.

Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Certain mice without specific receptors or mast cells don't lose hair from stress.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.

Mushrooms have beneficial properties for skin and hair care products and have great potential for future cosmetic use.

Dermoscopy helps diagnose and monitor treatment for hair loss from scarring conditions like discoid lupus and lichen planopilaris.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Advanced human skin models improve drug development and could replace animal testing.

Some Thai plants, especially Carthamus tinctorius, could help prevent hair loss and promote hair growth without adverse effects.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.