13 citations,
March 2020 in “Frontiers in cell and developmental biology” A substance called TCQA could potentially darken hair by activating certain genes and increasing melanin.
8 citations,
December 2017 in “Skin appendage disorders” WNT7A gene expression is higher in early stages of androgenetic alopecia, showing the role of WNT pathway, apoptosis, and inflammation in the disorder.
5 citations,
September 2016 in “Security science and technology” DNA can predict physical traits like eye and hair color accurately, especially in Europeans, but predicting other traits and in diverse populations needs more research.
5 citations,
February 2013 in “Expert Review of Dermatology” New acne treatments include combination creams, advanced retinoids, and light therapies, focusing on safety and patient adherence.
3 citations,
January 2019 in “Advances in stem cells and their niches” Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.
New treatments for vitiligo may focus on protecting melanocyte stem cells from stress and targeting specific pathways involved in the condition.
2 citations,
January 2023 in “International journal of biological sciences” Gray hair can potentially be reversed, leading to new treatments.
1 citations,
January 2017 in “Evolutionary studies” Different human traits like skin color and hair type vary between populations due to genetic adaptations to the environment.
1 citations,
January 2015 in “Journal of Pigmentary Disorders” Melasma is a skin condition linked to female hormones, genetics, UV exposure, and certain medications, but not to pituitary, adrenal, or thyroid diseases.
Acitretin treatment unexpectedly darkened a patient's gray hair.
March 2024 in “GSC Advanced Research and Reviews” Different light affects cell functions and can help treat skin conditions.
February 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Tandem repeats significantly influence hair color, especially darker shades, across different ancestries.
January 2021 in “Journal of clinical and cosmetic dermatology” Human skin responds to light with protective mechanisms, but more research is needed to understand these processes and their implications for health and therapy.
405 citations,
May 2007 in “Journal of The American Academy of Dermatology” Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.
75 citations,
January 2009 in “International journal of trichology” Hair grays due to oxidative stress and fewer functioning melanocytes.
58 citations,
June 2018 in “Scientific reports” Researchers found 15 new genetic links to skin traits in Japanese women.
49 citations,
June 2009 in “Seminars in Cutaneous Medicine and Surgery” The cosmetic industry should adapt to the varied beauty standards of ethnic groups and offer specialized treatments.
42 citations,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
41 citations,
December 2018 in “Experimental Dermatology” Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
24 citations,
January 2015 in “Evidence-based Complementary and Alternative Medicine” Polygonum multiflorum can promote hair growth when taken orally or applied topically.
16 citations,
July 2012 in “Current pharmaceutical biotechnology” New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
12 citations,
November 2020 in “Molecules” Carvone helps treat skin issues by reducing melanin and stopping harmful cell growth.
12 citations,
May 2018 in “JAAD Case Reports” A man's gray hair got darker and thicker after using a psoriasis drug.
7 citations,
February 2019 in “International Journal of Dermatology” Gray hair is caused by reduced melanin production or transfer issues, linked to aging and possibly health conditions, with treatments focusing on color camouflage.
5 citations,
May 2017 in “Journal of the European Academy of Dermatology and Venereology” The study found no significant difference in stress hormone levels between people with alopecia areata and healthy individuals, suggesting that the disease is not caused by an overactive stress response system.
4 citations,
March 2018 in “PloS one” Men with less sun-sensitive skin have lower PSA levels, while men with more sun-sensitive skin have higher PSA levels.
3 citations,
November 2023 in “Frontiers in cell and developmental biology” Melanocytes are important for skin and hair color and protect the skin from UV damage.
1 citations,
January 2016 in “Asian-Australasian journal of animal sciences” The protein Gnαs is found more in black mice than white mice and may influence their coat color.
1 citations,
July 2012 in “British Journal of Dermatology” New treatments and management strategies for skin conditions like melanoma and Spitz naevi were discussed at the dermatologists' meeting.
January 2024 in “GeroScience” Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.