June 2019 in “The Medical journal of Basrah University” This study found that laparoscopic ovarian drilling effectively decreased LH and testosterone levels, aiding fertility in PCOS patients nonresponsive to certain medications, without negatively impacting ovarian reserve.
August 2024 in “Medicine” This study found that medroxyprogesterone acetate and ethinyl estradiol with drospirenone were the most frequently prescribed medications for PCOS, with some patients experiencing drug changes or discontinuation due to side effects or therapeutic failure.
134 citations
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February 2005 in “Neuropsychopharmacology” GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.
11 citations
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January 2020 in “Epidemiology and Psychiatric Sciences” Antidepressants can cause long-term side effects like severe withdrawal symptoms and sexual dysfunction, which can last for months or years after stopping the medication.
3 citations
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February 2013 in “The Journal of Sexual Medicine” In this article, Irwig reported that sexual side effects of finasteride persist in 96% of patients even after stopping the medication, raising concerns about potential permanence.
1 citations
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October 2023 in “International journal of Ayurveda and pharma research” This source reviews various herbal remedies for treating hair loss, highlighting their potential benefits and reduced side effects compared to synthetic treatments, which often do not deliver lasting results and can cause adverse reactions.
1 citations
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January 1981 in “Elsevier eBooks” Melatonin stops melanin production after tyrosinase action, with cyclic GMP mimicking this effect.
March 2024 in “Tissue engineering. Part A” In this study, researchers observed that applying negative pressure to nude mice led to a significant increase in hair follicle growth and angiogenesis, suggesting potential for hair regeneration through mechanisms involving SOX-9, LHX-2, and β-catenin mediation.
February 2024 in “Trends in Sciences” This study examined the stability of two 5α-reductase inhibitors in Tectona grandis extracts, finding that they are more stable in acidic environments and degrade rapidly under heat and light unless protected, suggesting the need for careful storage when developing anti-hair loss medications.
October 2018 in “Springer eBooks” The document concludes that various topical medications are effective for skin conditions but often cause skin irritation as a side effect.
January 2025 in “Seizure” This study found that dual ASM therapies involving valproic acid were associated with poorer tolerability and specific adverse events, with cognitive side effects occurring prominently across all examined combinations.
September 2025 in “Clinical Case Reports” This case report identified a possible adverse effect of low-dose oral minoxidil for female pattern hair loss, as a 74-year-old woman developed significant dry mouth that resolved after stopping the medication and recurred upon rechallenge, suggesting a causal link.
November 2024 in “SKIN The Journal of Cutaneous Medicine” This study observed that patients with severe alopecia areata treated with baricitinib experienced increases in total cholesterol, LDL-C, and HDL-C, consistent with a JAK inhibitor class effect, but the mean increase was modest and lipid-lowering medication initiation was infrequent.
May 2024 in “Indian Journal of Pharmacology” In this case report, an 11-year-old girl with alopecia totalis initially treated with minoxidil experienced hypertrichosis, which reversed upon stopping the medication; hair regrowth on the scalp was achieved with tofacitinib after minoxidil discontinuation.
November 2025 in “Dermatology Reports” This review found that microinfusion of medications using tattoo devices (MMP®) shows potential as a minimally invasive method for treating ailments like alopecia and basal cell carcinoma, offering notable improvements with minimal side effects due to localized drug delivery.
This research reported that consuming sweetened tea drinks is linked to an increased risk of female androgenetic alopecia, with the effect significantly mediated by bedtime habits rather than daily sugar intake.
4 citations
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May 2025 in “Clinical & Experimental Allergy” This study confirmed omalizumab's safety but noted that hair loss was more prevalent than previously reported, with side effects influencing treatment decisions especially in patients with reduced medication effectiveness.
39 citations
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September 2015 in “Clinical Therapeutics” This review summarizes updated US prescribing information for teriflunomide in relapsing multiple sclerosis, highlighting its efficacy in reducing lesion activity and relapse rates but noting potential adverse effects such as headache and diarrhea.
5 citations
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January 2017 in “Nevrologiâ, nejropsihiatriâ, psihosomatika” In this study, sustained-release sodium valproate showed high efficacy in achieving seizure remission for adults with focal and generalized epilepsy over one year, but side effects like weight gain and tremor were more frequent among heterozygous carriers of certain gene variants.
18 citations
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October 2018 in “Journal of The American Academy of Dermatology” This review indicates that many former FDA category D and X systemic dermatologic medications may negatively impact male fertility, with further research needed to assess potential teratogenic effects.
4 citations
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January 2015 in “Case Reports in Urology” This case report describes a 66-year-old male with benign prostatic hyperplasia who developed urinary incontinence after starting venlafaxine, which resolved upon discontinuation of the medication.
January 2024 in “Journal of Ayurveda and integrative medicine” This paper discusses the potential of millets as a dietary intervention to help manage chemotherapy side effects in cancer patients, suggesting that their nutrient profile and various health benefits could support treatment without increasing medication burden.
75 citations
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November 1996 in “Fertility and Sterility” This study found that finasteride effectively reduced hirsutism in women during 12 months of treatment, with some effects persisting in the majority after stopping the medication.
May 2024 in “Lasers in medical science” In this retrospective study, a combined therapy of ablative fractional Er: YAG laser and medication was more effective in treating male androgenetic alopecia than medication alone, without causing serious adverse effects, as evaluated over 24 weeks.
March 2025 in “Journal of the American Academy of Dermatology” Low-dose oral minoxidil doesn't affect blood pressure in patients taking blood pressure meds.
166 citations
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October 2018 in “Endocrine Reviews” This review discusses the effects of hormonal treatments on the physical and mental health of transgender individuals, reporting significant reductions in mental health issues following treatment, but calls for more research on long-term and nonbinary outcomes.
16 citations
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July 1996 in “Dermatologic Clinics” This article discusses common dermatologic side effects of psychopharmacologic agents such as eruptions, urticaria, and photosensitivity, but it reports no new research findings.
March 2019 in “European Urology Supplements” This study found that metformin, insulin, and ACE inhibitors were associated with lower PSA levels, but statins did not decrease PSA, whereas low dose finasteride (1 mg) reduced PSA levels similarly to the higher 5 mg dose.
March 1983 in “International Journal of Dermatology” This paper discusses hypertrichosis as a side effect of minoxidil and does not present new clinical findings.
41 citations
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March 2017 in “PLoS neglected tropical diseases” This study found that isotretinoin, a drug commonly used for acne, inhibits polyamine transport in Trypanosoma cruzi, leading to trypanocidal effects, and suggests its potential as a treatment for Chagas disease without affecting mammalian cell viability.