May 2025 in “Journal of Dispersion Science and Technology” This study reported that a novel SMEDDS formulation of PPO demonstrated better permeation and improved hair growth compared to a marketed formulation in tests for managing androgenetic alopecia, with further exploration suggested.
July 2026 in “Lasers in Medical Science” In this study, the Peninsula Timerevert Needle was found to provide effective treatment for skin photoaging and acne scars with less pain and shorter treatment duration compared to EndyMed, although it caused more bleeding.
2 citations
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October 2025 in “Frontiers in Medicine” This study identified several previously unrecognized adverse events linked to ISO, including serious conditions such as Dandy-Walker syndrome and suicidal ideation, suggesting that safety measures and drug labeling should be updated.
2 citations
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May 2023 in “Current Nutrition Reports” This review summarizes various nutritional approaches and supplements, such as the Mediterranean and ketogenic diets and probiotics, as potential strategies to improve polycystic ovary syndrome symptoms, reporting no new clinical results.
1 citations
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June 2025 in “European Journal of Clinical Pharmacology” In this study, researchers found a statistically significant increase in reports of suicidality and depression associated with finasteride use, especially in younger individuals, whereas dutasteride showed no significant signal for suicidality and a weaker signal for depression.
March 2026 in “The Aging Male” This retrospective pharmacovigilance study reviewed adverse event reports from 2004 to 2025 for drugs treating benign prostatic hyperplasia, identifying distinct safety signals for α1-blockers, 5ARIs, and PDE5I, including some potential new adverse events that require further investigation.
December 2025 in “Archives of Dermatological Research” This study reported safety concerns regarding minoxidil, noting risks of infantile hypertrichosis linked to maternal exposure and associations with eye disorders among users in the general population.
September 2025 in “Therapies” This study found that finasteride is associated with significant depressive effects, including an increased risk of suicidality, which can persist beyond 20 months after stopping the medication, even without prior sexual dysfunction or psychiatric history.
4 citations
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January 2017 in “Ciência Rural” This case report highlights that equine multisystemic eosinophilic epitheliotropic disease should be considered in horses presenting with skin lesions and gastrointestinal symptoms, as illustrated by the progression in a 5-year-old horse despite treatment.
October 2025 in “Journal of the Endocrine Society” This case study reported that a 40-year-old woman with Graves' disease developed severe thrombocytopenia after starting methimazole, suggesting a rare but serious risk of methimazole-induced immune thrombocytopenia and underscoring the need for close monitoring.
July 2026 in “Materials Today Bio” This study demonstrated that in a mouse melanoma wound model, the MQ Microneedles effectively managed ROS levels to inhibit tumor growth and promote wound healing through light-controlled release.
January 2008 in “Journal of Clinical Dermatology” This study found that a new topical agent, Scalp medⓇ, significantly improved hair count and thickness in men with androgenetic alopecia after 24 weeks of treatment.
14 citations
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June 2016 in “Biomaterials” This study observed that MAA beads improved vascularization in non-diabetic male mice by modulating the Shh signaling pathway in wound granulation tissue, but showed no such effects in females.
September 2024 in “Journal of Cosmetic Dermatology” This study examined the FDA Adverse Event Reporting System database and found significant associations between low-dose oral minoxidil use and adverse events like pericardial effusion, highlighting the need for caution and recommending the use of the lowest effective dose until more safety data are available.
August 2026 in “Pharmacological Research - Modern Chinese Medicine” This review reports that microneedle systems can enhance the delivery and effectiveness of Traditional Chinese Medicine compounds in treating skin disorders, though most findings are based on preclinical studies and face challenges in translating to clinical practice.
August 2007 in “Pratica Medica & Aspetti Legali” This article discusses potential malpractice lawsuits linked to inadequate procedural steps in endoscopy, without reporting new research findings.
17 citations
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July 1988 in “International Journal of Dermatology” In this study, 2% minoxidil solution was found to be a safe and more effective treatment for early male pattern baldness compared to placebo.
This study found that Dex-loaded hyaluronic acid hydrogel microneedles significantly reduced pain in an acute inflammatory visceral pain model without sedation, suggesting a promising and patient-friendly alternative to intravenous delivery.
April 2022 in “Actas Dermo-Sifiliográficas” This study describes two cases of morning periorbital edema associated with low-dose oral minoxidil for androgenic alopecia, an effect infrequently reported in the literature.
39 citations
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February 2024 in “Small” This review discusses the evolution and development of smart and multifunctional microneedles, highlighting their potential future importance in medical applications, but it reports no new experimental results.
January 2026 in “Advances in Clinical and Experimental Medicine” This paper proposes a model integrating regulatory T cells and mesenchymal stem/stromal cells to enhance understanding of peripheral immune tolerance, suggesting their combined roles in immune regulation, autoimmunity pathophysiology, and potential MSC-based therapies.
30 citations
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June 2016 in “Journal of Human Genetics” This study found pathogenic mutations in genes EDA, EDA1R, and EDARADD in 101 out of 124 hypohidrotic ectodermal dysplasia patients, revealing 23 novel mutations and indicating genetic variability.
September 2022 in “JAAD Case Reports” This case report discusses rare but serious cardiac complications, including pericarditis and edema, observed with low-dose oral minoxidil for hair loss, highlighting the need for cautious prescribing, especially in high-risk patients.
15 citations
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June 2021 in “Medicina” This study found that combined intense pulsed light and low-level light therapy significantly improved ocular surface outcomes and quality of life for patients with meibomian gland dysfunction and dry eye disease.
1 citations
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May 2025 in “European Polymer Journal” This study developed a multifunctional dressing with the MeGel-SFSR composition, which showed faster healing and better tissue regeneration in diabetic wounds compared to controls, by utilizing a herbal compound and enhanced mechanical support, promoting hair follicle regeneration, collagen deposition, reduced inflammation, and vascularization in vivo.
10 citations
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July 2014 in “Annals of Saudi Medicine” This case report describes a rare concurrence of Morbihan disease with eyelid edema and extrafacial lupus miliaris disseminatus faciei in a patient, noting improvement of truncal lesions with roxithromycin and resolution of eyelid edema following surgical treatment.
2 citations
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July 2023 in “Journal of Education Health and Sport” This review article summarizes potential side effects of microneedle mesotherapy, including both infectious and non-infectious complications such as bruises, swelling, anaphylaxis, and skin necrosis, emphasizing that awareness and proper technique may mitigate these risks.
4 citations
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April 2011 in “International Journal of Radiation Biology” This study found that a newly developed mouse ear punch model effectively demonstrated that radiation significantly delays wound healing and may be used to study combined radiation and wound injury mechanisms.
43 citations
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August 2021 in “Journal of Orthopaedic Translation” This study explored a dual-functional dressing with quaternized chitosan and magnesium, finding it enhanced wound healing and had strong antibacterial effects against drug-resistant bacteria in diabetic rat models with infected foot ulcers, suggesting promise for diabetic foot ulcer treatment.
17 citations
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September 2022 in “Biomaterials Research” This study found that the film-trigger applicator system enhanced drug delivery efficiency and skin penetration of dissolving microneedles compared to traditional patch systems in both lab and animal models.