Understanding the Safety Profile of Topical Minoxidil: A Retrospective Review

    December 2025 in “ Archives of Dermatological Research ”
    J Suresh, Rohit Saxena, Vivekanandan Kalaiselvan
    Studysummary This study reported safety concerns regarding minoxidil, noting risks of infantile hypertrichosis linked to maternal exposure and associations with eye disorders among users in the general population.
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    Research cited in this study 11

    1. Contact Dermatitis Caused by Topical Minoxidil: Allergy or Just Irritation Acta Dermato Venereologica · 2025
    2. Minoxidil and Bilateral Central Serous Chorioretinopathy in an Adolescent Girl: Relationship or Causality? Romanian Journal of Ophthalmology · 2025
    3. Assessing the Safety of Topical Minoxidil Through Disproportionality Analysis of FAERS Reports Expert Opinion on Drug Safety · 2025
    4. The Psychological Consequences of Androgenetic Alopecia: A Systematic Review Journal of Cosmetic Dermatology · 2022
    5. Minoxidil: A Comprehensive Review Journal of Dermatological Treatment · 2021
    6. Minoxidil and Its Use in Hair Disorders: A Review [Corrigendum] Drug Design Development and Therapy · 2020
    7. Minoxidil Use in Dermatology, Side Effects, and Recent Patents Recent Patents on Inflammation & Allergy Drug Discovery · 2012
    8. Central Chorioretinopathy Associated with Topical Use of Minoxidil 2% for Treatment of Baldness Cutaneous and Ocular Toxicology · 2011
    9. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    10. Topically Applied Minoxidil May Cause Fetal Malformation: A Case Report Teratology · 2003
    11. Management of Severe Childhood Hypertension with Minoxidil: A Controlled Clinical Study The Journal of Pediatrics · 1977