2 citations
,
February 2023 in “International journal of molecular sciences” This study identified that copper depletion in dermal papilla cells reduced hair growth by boosting ROS levels, but ROS scavengers like NAC and ascorbic acid partially alleviated this effect.
6 citations
,
November 2018 in “Photodiagnosis and Photodynamic Therapy” This study found that using a wearable low-level light therapy device for photodynamic therapy significantly reduced actinic keratosis lesions and improved quality of life in patients with AK of the scalp.
May 2023 in “Elsevier eBooks” This article discusses scalp micropigmentation as a noninvasive method to conceal various forms of hair loss and scalp abnormalities and reports no clinical results; the authors highlight its safe and effective application.
October 2006 in “Urology” The study found that different criteria led to different patient groups in the CombAT study compared to the MTOPS study.
19 citations
,
February 2001 in “Journal of paediatrics and child health” This report documents a 14-year-old Chinese boy with mitochondrial encephalopathy, lactic acidosis, stroke-like episodes, and a de novo A3243G mitochondrial DNA mutation, highlighting the condition's multisystem involvement without ragged red fibers in muscle biopsy.
15 citations
,
October 2010 in “Archives of Toxicology” This study found that the yeast androgen screen (YAS) could detect the activity of methyltestosterone in urine for a longer period than classical GC/MS, potentially identifying long-lasting metabolites.
In this study, pilomatricoma, a benign skin tumor from hair follicle matrix cells, is highlighted as an important consideration when diagnosing painless, firm subcutaneous nodules, with accurate diagnosis relying on histopathological examination.
6 citations
,
July 2024 in “Journal of Cosmetic Dermatology” In this study, researchers found that a composition containing mannose-6-phosphate significantly reduced the total skin pore area by 24% in women after 56 days and by 30.2% in men after 7 days, suggesting its effectiveness in improving pore appearance by targeting dermal and epidermal modifications.
September 2024 in “Pigment Cell & Melanoma Research” This study found that mitochondrial fusion regulator Opa1 is crucial for maintaining melanocyte stem cells during the hair follicle cycle in mice, with Opa1 deficiency leading to impaired SCF-KIT signaling, reduced melanocyte populations, and early hair graying.
140 citations
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August 2010 in “Pigment Cell & Melanoma Research” This article discusses mouse genetic studies to explore factors influencing melanogenesis, highlighting pH and cysteine's roles, and proposes a hypothesis for human hair color diversity; it reports no new results.
100 citations
,
May 2006 in “American Journal Of Pathology” Matriptase is crucial for skin barrier, hair growth, and may contribute to skin cancer.
3 citations
,
August 2023 in “Biophysical Journal” In this study, researchers found that epithelial cells exhibit density-dependent metabolic heterogeneity, particularly in the pre-epithelial transition stage, where metabolic patterns correlate with cell proliferation and are influenced by actomyosin contractility.
2 citations
,
August 2004 This study found that early diagnosis using gas chromatography/mass spectrometry and appropriate long-term treatment are crucial for improving outcomes in patients with methylmalonic acidemia.
4 citations
,
January 2019 in “Skin appendage disorders” This study found that Follicular Maps, derived from trichoscopic images, remained consistent over time and unaffected by hair cycling or noncicatricial alopecia, offering a precise tool for diagnosing and monitoring hair and scalp conditions.
March 2026 in “Journal of Investigative Dermatology” This study found that GPT-4o demonstrated high concordance with in-person and image-based provider assessments in generating SALT scores for alopecia areata, suggesting its potential as an adjunct tool in clinical practice for automating these assessments.
5 citations
,
June 2020 in “Medicine” This report discusses a 22-year-old patient with MELAS syndrome carrying the m.10158T>C mutation, and highlights the need for extensive genetic testing when initial hot-spot mutation tests are negative.
19 citations
,
May 2001 in “Endocrinology” This study suggests that Mrp3 may play a role in both wound healing and the hair follicle cycle as a growth factor and/or angiogenesis factor.
10 citations
,
September 1997 in “Molecular carcinogenesis” This study found that mirex and TPA promote papilloma formation in CD-1 mouse skin through distinct populations of mutant Ha-ras cells, resulting in additive tumor yields.
16 citations
,
May 2000 in “Endocrinology” This study identified a new gene, mrp4, in mice, which suggests it may have a unique role in the growth and development of hair follicles in the ears and tails.
This pilot study employed in-vivo multiphoton microscopy to visualize pigment-producing melanocytes in vitiligo patients, aiming to enhance understanding of treatment impacts and potentially improve transplantation therapies.
2 citations
,
April 2024 in “Cosmetics” This study investigated non-laser methods for removing permanent makeup using plant extracts, testing their decolorization effects on mice through tattooing and electroporation techniques.
May 2024 in “Cell proliferation” This study found that melatonin supplementation significantly promoted hair regeneration in a hair depilation mouse model by up-regulating the Wnt/β-catenin signaling pathway in dermal papillae and hair follicle stem cells, suggesting potential implications for human hair loss treatments.
April 2024 in “Cellular signalling” This study on mice found that activating TRPML channels with MLSA1 promoted hair regeneration, accelerated hair cycle transition, and influenced human dermal papilla cells to secrete hair growth promoting factors while reducing hair growth inhibitors and oxidative damage.
January 1999 in “Journal of the European Academy of Dermatology and Venereology” RAPK is a rare skin disorder with pigmented spots, mainly on hands and feet, starting in youth.
August 2024 in “Clinical Case Reports” This case study reports on a rare benign skin tumor known as Pilomatricoma in the lower left orbital region of a 32-year-old male, highlighting its characteristic histopathological features and emphasizing the importance of surgical excision for successful treatment and minimal recurrence risk.
16 citations
,
March 2015 in “Clinical and experimental dermatology” This study found that mycophenolic acid promotes dermal papilla cell proliferation and anagen hair follicle induction in mice, suggesting potential as a treatment for hair-loss disorders.
61 citations
,
May 2016 in “Scientific reports” This study found that IMT-P8, a novel cell-penetrating peptide, effectively facilitated the dermal delivery of proteins and peptides in mouse skin and cell lines, suggesting potential for topical applications in cosmetics and skin diseases.
3 citations
,
November 2018 in “PubMed” This study evaluated shaved style scalp medical tattoo (SMT) in individuals with advanced hair loss, reporting high patient and surgeon satisfaction scores.
5 citations
,
July 2019 in “Photodiagnosis and photodynamic therapy” This study reports a case of a 59-year-old female with refractory follicular mucinosis and diffuse scalp alopecia who achieved complete clinical remission following treatment with a combination of topical tacalcitol and photodynamic therapy.
4 citations
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July 2024 in “Radiotherapy and Oncology” This study highlights that variations in clinical outcome reporting can undermine the validation of NTCP models for RIA, stressing the need for a standardized and objective scoring system.