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Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Shi-Bi-Man activates hair follicle stem cells and promotes hair growth by changing lactic acid metabolism and other cellular processes.

Four genes are potential markers for hair loss condition alopecia areata, linked to a specific type of cell death.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

The article suggests that targeting specific immune pathways could help control and treat the skin disease hidradenitis suppurativa.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Removing the ROBO4 gene in mice reduces skin inflammation and hair loss by affecting certain inflammation pathways and gene expression.

Hair follicles can help wounds heal faster and this knowledge could be used to treat chronic skin ulcers, with a potential use of a special stem cell hydrogel to enhance healing.

Skin aging reflects overall body aging and can indicate internal health conditions.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

Prolactin may be important for skin growth and immune function.

Researchers found four genes that could help diagnose severe alopecia areata early.

TNC+ fibroblasts play a key role in skin inflammation by interacting with T cells.

Treg cell-based therapies might help treat hair loss from alopecia areata, but more research is needed to confirm safety and effectiveness.

Wound healing is a complex process involving different cells and stages, leading to scar tissue formation and strength increase over time.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Hydrogels could lead to better treatments for wound healing without scars.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Fat stem cells from diabetic mice can still help heal wounds.

A substance called TCQA could potentially darken hair by activating certain genes and increasing melanin.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

Stuff from umbilical cord stem cells helps skin heal and look younger.

Botulinum toxin may help reduce stress-related hair loss.

The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.

New treatments for skin and hair repair show promise, but further improvements are needed.

Targeting and modifying the stem cell niche can improve regenerative therapies.