January 2015 in “Farmatsevtychnyĭ zhurnal” This research discusses the development of a complex tincture for telogen effluvium using nettle, sage, and chestnut leaves, but provides no new clinical results.
In this study, researchers formulated and evaluated herbal hair serums incorporating natural ingredients like flax seed, fenugreek, and castor oil, finding that the best formulation supported hair growth with minimal side effects compared to existing herbal serums.
24 citations
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December 2014 in “International Journal of Molecular Medicine” In this study, researchers found that petroleum ether extract of Eclipta alba significantly stimulated follicular keratinocyte proliferation and reduced TGF-β1 expression in nude mice, suggesting potential use for certain types of alopecia.
September 2017 in “World journal of Pharmacy and pharmaceutical sciences” In this study, researchers observed that a polyherbal ointment made from specific plant extracts significantly promoted hair growth in rats compared to ointments with single extracts, possibly due to the presence of flavonoids and tannins.
September 2025 in “International Journal for Research in Applied Science and Engineering Technology” In this study, researchers developed an herbal hair tonic using ingredients like coconut oil, aloe vera, and neem, and evaluated its antibacterial, antifungal, and hair strength-enhancing properties, though specific results are not reported.
January 2025 in “NATIONS UNIVERSITY INTERNATIONAL JOURNAL OF MULTI-DISCIPLINARY STUDIES” This study focused on the formulation of topical gels containing Equisetum arvense extract, evaluating their consistency and preparation using gelling agents for potential application in enhancing drug delivery to wound sites.
1 citations
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October 2015 in “The Pharma Innovation Journal” This study found that the optimal method to introduce Saw Palmetto extract into emulsion bases for androgenic alopecia treatment involves mixing it with 48% ethanol at the end of the formulation process.
This study reports that Hair RiseTM microemulsion, made from plant extracts, significantly enhanced hair follicle cell growth and improved hair growth signaling pathways, suggesting it as a plant-based alternative for androgenetic alopecia treatment.
8 citations
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January 2014 in “BioMed Research International” This study reported that among three plant extracts tested for hair growth on nude mice, Eclipta alba significantly increased hair density and length, unlike Asiasari radix and Panax ginseng.
November 2024 in “Journal of Cosmetic Dermatology” This study observed that a topical serum containing Silybum marianum extract, manganese PCA, and Lespedeza capitata extract enhanced hair follicle growth and hair shaft elongation, while prolonging the anagen phase in an ex vivo human scalp skin model, suggesting potential benefits for hair loss treatment.
15 citations
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January 2009 in “Journal of chemical and pharmaceutical research” This study found that a herbal hair oil formulation with 7.5% concentration of each active ingredient, prepared using the boiling method, showed excellent hair growth activity comparable to 2% minoxidil.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed and evaluated a polyherbal hair growth serum using natural ingredients like fenugreek, rosemary, and hibiscus, and found it to be a stable, effective, and safe alternative to synthetic hair care products, with good user compliance from its roll-on applicator.
August 2024 in “Proceeding Cendekia International Conference Health and Technology” In this quasi-experimental study, researchers explored the optimal formulation of a nanoemulsion containing candlenut ethanol extract, finding that specific combinations of tween 80, span 80, and sonication time affected its physical properties and stability, although further activity testing is needed.
August 2018 in “Farmatsevtychnyĭ zhurnal” This study developed an emulgel containing Saw Palmetto extract and Sophora Japonica tincture for treating androgenic alopecia, optimizing its preparation process to enhance dispersion and rheological properties.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study outlines the potential benefits of a formulated herbal hair serum containing ingredients like black seed, ginger, and almond oil, highlighting its ability to improve scalp health, promote hair growth, reduce hair fall, and enhance hair shine and manageability.
January 2026 in “Dermatologic Therapy” This study found that a hair serum containing Acanthus ebracteatus extract improved hair regrowth in men with androgenic alopecia, increasing hair count and density of anagen hairs over a 6-month period, with combination treatments showing early effectiveness.
November 2025 in “Essential Chem” In this study, Eclipta alba extract showed potential for hair regrowth by increasing the proliferative activity of human dermal papilla cells by 45% in vitro, with evidence suggesting activation of the Wnt signaling pathway.
2 citations
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August 2019 in “Journal of drug delivery and therapeutics” This study reports the formulation and evaluation of an herbal shampoo, "Herbello", aimed at improving antidandruff activity using various natural ingredients.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated a polyherbal Ayurvedic hair regrowth oil containing various plant extracts and found that the F2 formulation significantly enhanced hair growth in albino rats, suggesting potential for promoting hair growth and scalp health in humans, though further clinical testing is needed.
6 citations
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January 2018 in “Research Journal of Topical and Cosmetic Sciences” In this study, researchers developed an herbal liquid shampoo using ingredients like shikekai and tulsi powder, aiming for safety and efficacy without the damaging effects of chemical alternatives, and found that it could clear dandruff and dirt while enhancing hair strength and growth.
11 citations
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May 2021 in “Asian Journal of Pharmaceutical and Clinical Research” This review summarizes the phytomedicinal importance of Eclipta alba in Ayurvedic and folk medicine, particularly its use for hair growth and various biological properties, without reporting new clinical results.
4 citations
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March 2016 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that a self-emulsifying formulation with eugenol in emu oil improved hair conditioning and growth in rats, showing rapid hair increase after an initial delay compared to minoxidil.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed a polyherbal hair growth serum containing natural ingredients such as fenugreek, rosemary, and hibiscus, and found it to be safe and effective in promoting hair growth, improving scalp health, and reducing hair fall while being stable over time.
This study characterized Eclipta alba for use in a capillary product for alopecia, confirming its suitable physico-chemical properties and pharmacological constituents, including wedelolactone for hair growth.
December 2018 in “Jurnal Farmamedika (Pharmamedica Journal)” This study found that a combination of ethanol extract from watermelon white skin and liquid from kepok banana tree trunk resulted in greater hair growth length in rats compared to Minoxidil.
April 2025 in “International Journal For Multidisciplinary Research” This study formulated a nano-herbal hair spray using neem, fenugreek, and amla extracts combined with chitosan nanoparticles, finding it enhanced hair elasticity, breakage resistance, and provided antibacterial protection, suggesting it as an effective natural alternative to traditional hair treatments.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study focused on developing and evaluating a herbal hair growth serum made from natural ingredients, aimed at improving scalp health, strengthening hair follicles, and promoting hair growth, suitable for daily use without the adverse effects associated with synthetic products.
3 citations
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June 2010 in “Pharmacognosy journal” This study found that a formulated polyherbal antidandruff hair oil containing eucalyptus and ocimum volatile oils, along with hibiscus and phyllanthus extracts, showed both antifungal and hair growth activities in open pilot clinical trials.
October 2025 in “Research Journal of Topical and Cosmetic Sciences” This study evaluated a herbal scalp serum containing Phyllanthus Emblica, hibiscus, Vitamin E, aloe Vera, and citrus oil, finding it stable and possessing good antibacterial activity.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights a polyherbal hair formulation that combines various natural ingredients, reporting potential benefits in improving scalp circulation, strengthening hair, and promoting regrowth, which might offer a safer alternative for managing male pattern baldness compared to synthetic drugs.