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The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

VEGF helps hair grow and determines follicle size by increasing blood vessel growth.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Fat-related cells are important for initiating hair growth.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Targeting colon cancer stem cells might lead to better treatment results.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.

A protein from certain immune cells is key for new hair growth after skin injury in mice.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Androgens can cause hair growth in some areas and hair loss on the scalp.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Stem cell self-renewal is complex and needs more research for full understanding.

Cathepsin L is essential for normal hair growth and development.

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Different types of stem cells and their environments are key to skin repair and maintenance.