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    Glossary Microenvironment

    localized environment surrounding cells or tissues

    The term "microenvironment" refers to the specific, localized environment surrounding cells or tissues, including factors like nutrients, oxygen levels, and signaling molecules. In the context of hair and alopecia, the hair follicle microenvironment includes the cells, extracellular matrix, and biochemical signals that influence hair growth and health. Understanding this microenvironment is crucial for developing treatments for hair loss conditions.

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    1. Macroenvironmental Regulation of Hair Cycling and Collective Regenerative Behavior Cold Spring Harbor Perspectives in Medicine · 2014 · 42 citations
    2. Aging in hair follicle stem cells and niche microenvironment The Journal of Dermatology · 2017 · 38 citations
    3. Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth Proceedings of the National Academy of Sciences of the United States of America · 2013 · 256 citations
    4. Microenvironmental reprogramming of thymic epithelial cells to skin multipotent stem cells Nature · 2010 · 116 citations
    5. Microenvironmental reprogramming of human dermal papilla cells for hair follicle tissue engineering Acta Biomaterialia · 2022 · 45 citations
    6. Local Microenvironment Provides Important Cues for Cell Differentiation in Lingual Epithelia PloS one · 2012 · 6 citations
    7. Dissecting the microenvironment around biosynthetic scaffolds in murine skin wound healing bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 2 citations
    8. Repigmentation Competence in Vitiligo: Integrating Immune, Regulatory, Regenerative, and Microenvironmental Axes Journal of Personalized Medicine · 2026
    9. Microenvironmental Dysregulation in Androgenetic Alopecia: Molecular Pathways and Translational Implications for Regenerative Therapies Zenodo (CERN European Organization for Nuclear Research) · 2026
    10. Microenvironmental Dysregulation in Androgenetic Alopecia: Molecular Pathways and Translational Implications for Regenerative Therapies Zenodo (CERN European Organization for Nuclear Research) · 2026
    11. Microenvironmental Dysregulation in Androgenetic Alopecia: Molecular Pathways and Translational Implications for Regenerative Therapies Zenodo (CERN European Organization for Nuclear Research) · 2026
    12. Microenvironment-Responsive Recombinant Collagen XVII-Based Composite Microneedles for the Treatment of Androgenetic Alopecia Acta Biomaterialia · 2025
    13. Nanoscale microenvironment engineering for expanding human hair follicle stem cell and revealing their plasticity Journal of Nanobiotechnology · 2021 · 15 citations
    14. The Skin Microenvironment: A Dynamic Regulator of Hair Follicle Development, Cycling and Disease Biomolecules · 2025
    15. Bioengineering a humanized acne microenvironment model: Proteomics analysis of host responses to <i>Propionibacterium acnes</i> infection <i>in vivo</i> PROTEOMICS · 2008 · 40 citations
    16. Ceria Nanozyme-Integrated Microneedles Reshape the Perifollicular Microenvironment for Androgenetic Alopecia Treatment ACS Nano · 2021 · 38 citations
    17. TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia Cell Death and Disease · 2016 · 38 citations
    18. An injectable photocuring silk fibroin-based hydrogel for constructing an antioxidant microenvironment for skin repair Journal of Materials Chemistry B · 2024 · 15 citations
    19. A Honey Trap for the Treatment of Acne: Manipulating the Follicular Microenvironment to Control<i>Propionibacterium acnes</i> BioMed research international · 2013 · 9 citations
    20. Single‐cell RNA sequencing highlights the role of proinflammatory fibroblasts, vascular endothelial cells, and immune cells in the keloid immune microenvironment International Journal of Dermatology · 2024 · 6 citations
    21. Epidermal stem cells: Interplay with the skin microenvironment during wound healing Molecules and Cells · 2024 · 5 citations
    22. Targeting the Hypoxic Microenvironment in Cutaneous Chronic Graft-Versus-Host Disease through PI3Kδ Inhibition Blood · 2024 · 1 citations
    23. Taurine‐based Active Pharmaceutical Ingredient Ionic Liquids Modulate the Perifollicular Microenvironment for Androgenic Alopecia Treatment Advanced Healthcare Materials · 2026
    24. Hafnium Oxide Nanostructure-IntegratedSilk FibroinMicroneedles Reshape Cutaneous Melanocyte Microenvironment for VitiligoTherapy Figshare · 2026
    25. Immune Microenvironment of Hair Follicles in Tumor Immunotherapy ImmunoTargets and Therapy · 2026
    26. Bioadhesive Polydopamine-Vitamin A Derivative Hydrogels Reprogram the Wound Microenvironment for Scarless Wound Healing and Hair Follicle Regeneration Materials Horizons · 2026
    27. Hair Growth Promoting Effects of Kesh-Kanti-Expert-Oil are Mediated Through Keratinocyte Proliferation and Modulation in Follicular Microenvironment Pharmacological Research - Natural Products · 2025
    28. Cold Atmospheric Plasma‐Activated In Situ Hydrogel Induces Hair Regeneration Via Immune Microenvironment Remodeling Advanced Science · 2025
    29. Remolding Microenvironmental Homeostasis for Enhancing Regenerative Hypertrophic Scar Treatment Based on Functionalized Microneedles Interdisciplinary materials · 2025
    30. Terminalia bellirica (Gaertn.) Roxb. extracts reshape the perifollicular microenvironment and regulate the MAPK pathway for androgenetic alopecia treatment Journal of Ethnopharmacology · 2024