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Stem cells in mouse nails are found in the nail matrix and may control nail growth.

This study suggests that miRNAs, particularly miR-195-5p, may regulate the loss of hair follicle inductivity in cultured dermal papilla cells by suppressing the Wnt/β-catenin pathway.

This study found that ISX9 may activate the Wnt/β-catenin signaling pathway and holds potential as a therapeutic agent for treating alopecia.

This study developed a potent Wnt surrogate with high specificity for the Fzd7 receptor in mice, promoting full hair follicle regeneration and robust hair growth, suggesting potential applications in tissue development and targeted regeneration.

This study identified ISX9 as a novel agonist of the Wnt/β‐catenin pathway, which promoted hair regrowth in mice and may offer a therapeutic approach for alopecia.

This research observed that Salvianolic acid B (Sal B) significantly promoted hair regeneration in vivo and in vitro, outperforming minoxidil in a mouse model of androgenetic alopecia, by activating Wnt/β-catenin and mTORC2/Akt pathways and upregulating MMPs and MAPKs.

This study found that the protein CCN2 in dermal papilla cells is a physiologically relevant suppressor of hair follicle formation by destabilizing β-catenin, which may help maintain stem cell quiescence.

This study found that p2y5 functions as a novel LPA receptor involved in the G13-Rho signaling pathway, with implications for human hair growth, and proposes renaming it to LPA6.

This article reviews the role of R-spondins and their receptors in bone development and metabolism, highlighting their potential modulatory effects and clinical implications for treating bone loss diseases, but reports no new clinical results.

Sfrp2 increases during hair follicle catagen phase and slows keratinocyte growth.

This review discusses the varied roles of Wnt7a in development, tissue homeostasis, and cancer, reporting no clinical results; the authors emphasize the need for further investigation on its roles in inflammation and fibrosis.

This study found that inhibiting the interaction between CXXC5 and Dishevelled could stimulate hair regrowth in mouse models by enhancing WNT/β-catenin signaling, suggesting a potential therapeutic strategy for hair loss involving compounds that block this interaction, such as interfering short peptides.

This study identified differentially expressed miRNAs between the telogen and anagen phases of hair growth in Wan Strain Angora rabbits, contributing to understanding miRNA-mediated regulation of rabbit hair follicle cycling.

This study reports that Wise is expressed in specific patterns during the morphogenesis of chick embryos, particularly in regions associated with known signaling molecules like Wnt, Bmp, and Shh.

This study found that a phosphorus starvation-insensitive mutant of Arabidopsis thaliana shows altered root growth and auxin responses under low phosphate conditions compared to wild-type plants, suggesting a role for LPR1 in regulating these traits.

A feedback loop between LRH and RSL4 controls root hair growth in Arabidopsis.

This review discusses newly identified non-Edg family lysophosphatidic acid receptors, detailing their roles in vascular development, platelet activation, and hair growth, and reports no clinical results.

This study used cryoelectron microscopy to unveil the structure of LPA-bound human LPAR6, revealing unique ligand binding and recognition modes distinct from LPAR1, which may aid in designing targeted compounds for hair loss and cancer.

This review summarizes how genetic studies using conditional β-catenin loss- and gain-of-function mice have advanced understanding of canonical Wnt signaling's role in embryonic development, adult stem cell maintenance, and cancer modeling.

This review discusses the roles of key developmental signaling pathways in mammalian skin repair compared to skin development, and suggests these insights could lead to better wound healing therapies, but it reports no new findings.

This study found that hair follicles in mice and humans can convert wound-related myofibroblasts into adipocytes, suggesting a potential pathway to reduce scar formation by activating BMP signaling.

This review discusses the role of TGF-β signaling in stem cell recruitment and tissue regeneration, indicating that abnormalities in TGF-β activation contribute to various major diseases and suggesting avenues for therapeutic intervention.

This review summarizes the roles of Wnt signaling in wound healing but presents no new clinical findings, suggesting potential for Wnt-based therapies to enhance tissue regeneration.

This article reviews the complex signaling pathways between epithelial and mesenchymal cells crucial for hair follicle morphogenesis, highlighting the Wnt pathway's role as a master regulator without reporting new experimental findings.

This review discusses the regulation and function of vitamin D and its receptor in skin cells, highlighting their roles in processes such as proliferation inhibition, differentiation, and innate immunity, but reports no new results.

The researchers reported that DHT-inducible DKK-1 may play a significant role in DHT-driven balding by inhibiting hair follicle cell growth and promoting apoptosis in androgenetic alopecia.

This study observed that applying JAK-STAT pathway inhibitors to mouse and human skin led to rapid hair growth by inducing the anagen phase of hair follicles.

This review examines the functions of vitamin D and its receptor in skin and explores how these are regulated, reporting no new clinical results.

This review discusses the WNT signaling pathway's involvement in human diseases and highlights recent advances in WNT-related treatments, but it presents no new research findings.

This review summarizes the current understanding of Wnt signaling in relation to its roles in tissue regeneration and cancer progression and discusses recent medical advancements targeting this pathway for therapeutic purposes.