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The study concluded that a higher waist-hip ratio significantly increases the risk of metabolic syndrome in women with PCOS.

The document concludes that managing PCOS requires a comprehensive approach, including lifestyle changes and medication, to improve symptoms and reduce health risks.

The document concludes that skin and nail changes can indicate various underlying health conditions.

Good nutrition is crucial for health and preventing disease, and supplements can help prevent nutrient deficiencies.

Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.

The document concludes that managing Dunnigan-Type Familial Partial Lipodystrophy involves treating associated health issues and using medications like metformin and leptin replacement.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Bergamot may improve heart health, skin conditions, and mood, but more research is needed to confirm these benefits.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

Managing side effects of endocrine therapy is crucial to improve adherence and survival in breast cancer patients.

Surgery to lower high testosterone in postmenopausal women with certain ovarian tumors doesn't significantly affect their metabolism.

New treatments for PCOS focus on managing symptoms and improving fertility.

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.

The document explains various skin conditions and their treatments.

The Rotterdam Study investigates diseases in older adults and has produced many research findings.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

PCOS is a long-term condition that needs more research for better understanding and treatment.

Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.