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Mutations in the LSS gene cause a rare type of hereditary hair loss.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Panax ginseng is generally safe with mild side effects and may have health benefits, but more research is needed.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

Eclipta prostrata has many traditional uses and health benefits, but more research is needed to understand how it works and ensure it's safe.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

People with polycystic ovary syndrome may have a higher risk of heart problems due to abnormal nervous system control of their heart and blood pressure.

*Acorus calamus* has many medicinal benefits but needs more safety research.

Women with PCOS are more likely to have fatty liver disease, especially if they have metabolic problems.

Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.

Hormonal therapies are safe and effective for treating adult women's acne.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Isotretinoin is safe and effective for acne, with common side effects like dry lips; serious side effects are rare.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.