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Combining letrozole with metformin is the most effective treatment for inducing pregnancy in women with PCOS.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

The Rotterdam Study investigates diseases in older adults and has produced many research findings.

The Rotterdam Study aims to understand various diseases in older adults.

Generalized pustular psoriasis patients often need strong medication and careful treatment due to flare-ups and complications.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Lower SHBG levels may increase the risk of PCOS.

Female Pattern Hair Loss affects women's self-esteem and needs more research for better treatment.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Despite progress, better treatments and understanding are needed for the high rates of long-term issues and deaths linked to eating disorders.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Neurosteroids show promise for treating epilepsy and more research is needed.

Spironolactone helps reduce pain and lesions in hidradenitis suppurativa patients, and lower doses are also effective.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

Hormonal therapies are safe and effective for treating adult women's acne.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

Young women with PCOS have a higher risk of high blood pressure and metabolic syndrome, but these risks may decrease after age 40.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.

Early diagnosis and treatment are key to managing health risks in teens with PCOS.

No link found between new male baldness genes and female hair loss.

17α-Estradiol solution safely improves hair density and thickness in female pattern hair loss.

Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.

The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.