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Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Current treatments for alopecia show no significant long-term benefits.

Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.

The conclusion is that FFA and LPP have similar scalp biopsy features, making them hard to distinguish histologically, and FFA may be a specific kind of scarring hair loss.

The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

The treatment helped reduce symptoms and stabilize the hairline in most patients with Frontal Fibrosing Alopecia, but hair regrowth was limited.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

Trichoscopy helps diagnose and monitor alopecia areata by looking at a combination of specific hair and scalp features.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

The Lexington LaserComb helped regrow hair in mice with a condition similar to human hair loss.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Minoxidil can help regrow hair in alopecia areata patients.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

The document concludes that early recognition and treatment of primary cicatricial alopecia is crucial to prevent permanent hair loss.

Scalp cooling can prevent chemotherapy-induced hair loss, and certain treatments can speed up hair regrowth, but more research is needed for better treatments.

Oral dutasteride can potentially treat frontal fibrosing alopecia in postmenopausal women, with some patients showing disease arrest and hair regrowth.

People with alopecia areata have more Th17 cells and fewer Treg cells, which may be key to the condition's development.

The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Both mouse and rat models are effective for testing alopecia areata treatments.

Vitamin D receptor is crucial for starting hair growth after birth.

Minoxidil helps hair regrowth in alopecia areata safely.

Tofacitinib was effective in treating hair loss in two patients with alopecia universalis.

Topical immunotherapy, especially with DPCP, is effective for treating severe alopecia areata.

Combining diphenylcyclopropenone with anthralin is more effective for hair regrowth in alopecia areata than using diphenylcyclopropenone alone, but may cause more side effects.

Hair breakage may be an early sign of a hair loss condition called CCCA in African American women.