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research Transient stimulation of TRPMLs enhance the functionality of hDPCs and facilitate hair growth in mice
This study on mice found that activating TRPML channels with MLSA1 promoted hair regeneration, accelerated hair cycle transition, and influenced human dermal papilla cells to secrete hair growth promoting factors while reducing hair growth inhibitors and oxidative damage.
research Coexistence of Lichen Planus Pigmentosus and Classic Lichen Planopilaris: A Case Report and Literature Review
This article reports a rare case of a postmenopausal woman with coexisting lichen planus pigmentosus and classic lichen planopilaris, alongside a review of related literature.
research Lentiginosis within plaques of linear atrophoderma of Moulin: a twin-spotting phenomenon?
This article reports on lentiginosis observed within plaques of linear atrophoderma of Moulin and discusses its potential classification as a twin-spotting phenomenon but provides no new clinical research results.
research Autosomal Recessive Woolly Hair Caused by LIPH Mutations: A Case Series of Six Chinese Patients
LIPH mutations cause woolly hair in some Chinese people.
research Non-Edg family LPA receptors: the cutting edge of LPA research
This review discusses newly identified non-Edg family lysophosphatidic acid receptors, detailing their roles in vascular development, platelet activation, and hair growth, and reports no clinical results.
research Commentary: Treatment of lichen planopilaris
This article discusses the efficacy and safety of mycophenolate mofetil and hydroxychloroquine for treating lichen planopilaris and reports no new clinical results.
research Isolated autosomal recessive woolly hair/hypotrichosis: genetics, pathogenesis and therapies
This study suggests that topical minoxidil may be a promising treatment for isolated autosomal recessive woolly hair due to LIPH mutations, although effective treatments are not yet established.
research Lupus Eritematosus Sistemik pada Pria
This case report describes a 29-year-old man with systemic lupus erythematosus who responded well to pulse-dose methylprednisolone treatment.
research Automated Monkeypox Identification from Electronic Medical Records Using Large Language Models — Shenzhen City, Guangdong Province, China, 2023–2025
This study explored using large language models to automatically identify monkeypox cases from electronic medical records, finding that models based on DeepSeek features performed better than traditional methods, with logistic regression showing high accuracy in detecting key symptoms like fever and rash.
research Medical Reasoning with Large Language Models: A Survey and MR-Bench
This review presents a comprehensive evaluation of medical reasoning using large language models, highlighting a significant gap between exam-level performance and true clinical decision-making accuracy.
research Mrp3, a Mitogen-Regulated Protein/Proliferin Gene Expressed in Wound Healing and in Hair Follicles
This study suggests that Mrp3 may play a role in both wound healing and the hair follicle cycle as a growth factor and/or angiogenesis factor.
research Dimethylsiloxane polymers for the effective transdermal delivery of Minoxidil in hair loss treatment
This study reported that a new polymeric formulation for topical minoxidil delivery in an animal model improved hair growth and hair follicle formation more effectively than minoxidil in PBS, suggesting potential as a future hair loss treatment.
research Wavelength-encoded laser particles for massively-multiplexed cell tagging
This study introduced laser particles as a new imaging probe capable of real-time tracking of thousands of individual cells in 3D tumor models, suggesting potential for advanced single-cell analyses.
research Autonomous In Situ Biointerfacing Platform for Real-Time Electrophysiological Monitoring and Advanced Wound Management
This study developed the TLMG hydrogel, a seamless in situ biointerface platform, demonstrating robust adhesion, high conductivity, and therapeutic effects for intelligent wound management in complex animal models and human tests, indicating its promise for integrated bioelectronic medicine.
research Evaluation of hair surface structure and morphology of patients with lichen planopilaris (LPP) by atomic force microscopy (AFM)
This study used atomic force microscopy to identify significant morphological differences in hair from patients with lichen planopilaris compared to healthy controls, noting more scratches, uneven edges, and pitted scales in affected hair, which may aid future research on the condition.
research My Clinical Experience with Needle and Laser SMP Devices
This article reviews non-surgical hair loss treatments and procedures, highlighting options like minoxidil, DHT inhibitors, and laser light therapy, and reports no new clinical findings.
research Lichen planus pigmentosus and lichen planopilaris
This review discusses the potential relationship between lichen planus pigmentosus and frontal fibrosing alopecia, presenting a case study but reporting no new clinical findings.
research Morbihan disease and extrafacial lupus miliaris disseminatus faceie: a case report
This case report describes a rare concurrence of Morbihan disease with eyelid edema and extrafacial lupus miliaris disseminatus faciei in a patient, noting improvement of truncal lesions with roxithromycin and resolution of eyelid edema following surgical treatment.
research WISP-1 induced by mechanical stress contributes to fibrosis and hypertrophy of the ligamentum flavum through Hedgehog-Gli1 signaling
This study found that mechanical stress activates a WISP-1/Hedgehog signaling axis that contributes to ligamentum flavum hypertrophy and fibrosis, identifying Hedgehog signaling as a potential therapeutic target.
research Follicular mycosis fungoides associated with lithium
This case report suggests that lithium, either alone or with haloperidol, may induce skin changes resembling follicular mycosis fungoides.
research Lupus erythematosus. What’s new?
This case report highlights the complexity of lupus erythematosus/lichen planus overlap syndrome, noting a high potential for progression to systemic lupus erythematosus.
research Prevalent founder mutation c.736T>A of LIPH in autosomal recessive woolly hair of Japanese leads to variable severity of hypotrichosis in adulthood
This study observed that some patients with homozygous c.736T>A mutation in LIPH may have mild hypotrichosis with long hairs in adulthood.
research BH09 Mycophenolate mofetil in the management of lichen planus pigmentosus in a woman with frontal fibrosing alopecia
In this case study, a woman with frontal fibrosing alopecia and associated hyperpigmentation showed significant improvement in skin pigmentation and itch after 9 months of treatment with mycophenolate mofetil, highlighting its therapeutic potential for lichen planus pigmentosus linked to this condition.
research 311 Single-cell transcriptomics reveals distinct molecular programs in folliculotropic mycosis fungoides
This study revealed distinct cellular and transcriptomic differences among various subtypes of cutaneous T-cell lymphoma, particularly highlighting characteristics unique to folliculotropic mycosis fungoides.
research Hematological and immune homeostasis of experimental animals under the influence of lotion, containing 5% minoxidil
This study found that a lotion with 5% minoxidil significantly altered immune parameters and disrupted immunological balance in guinea pigs, suggesting a substantial impact on both cellular and humoral immunity.
research 707 Chromatin remodeler Lymphoid-specific helicase (Lsh) is a critical determinant controlling postnatal epidermal growth, differentiation and response to injury
This study reported that the absence of Lsh in skin led to significant epidermal hyperplasia and altered gene expression, suggesting its crucial role in regulating epidermal proliferation, differentiation, and wound healing.
research Evaluating anti-LGBTQIA+ medical bias in large language models
This study found that all four evaluated large language models generated a significant proportion of inappropriate responses when prompted with or without LGBTQIA+ identity terms, with more severe bias observed in prompts mentioning LGBTQIA+ identities.
research Low-Level Laser Therapy: A Comprehensive Review of Anti- Inflammatory Applications and Therapeutic Potential
This review discusses various applications of low level laser therapy and argues for a holistic evaluation of patients but reports no new clinical findings.
research Oral lichen planus preceding concomitant lichen planopilaris
This study reports the first known case of oral lichen planus preceding lichen planopilaris in a patient, highlighting a possible sequential relationship between the conditions.