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Phthirusa pyrifolia extract may lower testosterone and harm male rat reproduction without damaging the liver or kidneys.

The patient recovered well and returned to college without any lasting issues.

Green tea extract may increase copper levels in mouse hair without affecting liver copper.

Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.

Finasteride affects brain stress and enzyme activity differently in various regions, possibly helping with liver-related brain issues.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

L-cystine, D-pantothenat, and miliacin together significantly boost keratinocyte growth and metabolism.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

Isotretinoin is safe and effective for acne, with common side effects like dry lips; serious side effects are rare.

A young Saudi girl with uncontrolled type 1 diabetes and hypothyroidism had two rare conditions, Mauriac syndrome and Van Wyk–Grumbach syndrome.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.

A rabbit with sebaceous adenitis was effectively treated with ciclosporin and medium-chain triglycerides.

Deferasirox combined with sorafenib reduces liver cancer risk and lessens treatment side effects.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Green tea extract may help reduce excessive hair growth.

Finasteride and dutasteride may cause metabolic issues like liver disease and diabetes.

Ziziphus spina-christi leaf extract lowered blood sugar and protected organs in diabetic rats.

Metformin may help regulate periods and cause modest weight loss in PCOS patients, but more research is needed.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Finasteride effectively treats baldness but may cause sexual side effects.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.