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The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.

Transfollicular drug delivery is promising but needs more research to improve and understand it better.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Squarticles, tiny particles made from sebum-derived lipids, can effectively deliver minoxidil, a hair growth drug, directly to hair follicles and skin cells, with less skin penetration and more tolerability.

Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.

Lipase H is important for hair follicle function and shaping hair fibers.

Patients with GATA2 deficiency show early skin symptoms that help diagnose the condition.

Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.

Obese Hispanic women with PCOS are at higher risk for metabolic problems than non-Hispanic white women.

A new mutation in the AGPAT2 gene causes severe fat tissue loss and related health issues by reducing the protein's levels.

A rare skin disorder, Ichthyosis with confetti, has no cure but treatment focuses on managing symptoms with moisturizers.

Hypothyroidism in dogs is usually caused by immune system issues or gland atrophy, affects middle-aged purebreds most, and is treatable with medication.

Get head MRI for babies with achondroplasia early, use free immunoglobulin light chains to detect certain neurodevelopmental disorders, and video calls work for speech therapy in patients with facial anomalies.

Men with a certain type of hair loss often use facial moisturizers, and a specific antibiotic treatment may help another hair condition.

The chapter explains that there are many genetic skin disorders affecting skin cell formation, including both common and rare types.

Skin symptoms are important for diagnosing infections in children.

Oral spironolactone and isotretinoin are effective for treating acne.

Young HS patients often have other physical and mental health issues, and research on HS covers a wide range of topics including genetics, triggers, treatments, and the need for more data.

New guidelines stress early diagnosis and lifestyle changes to manage metabolic syndrome and prevent complications.

A man's unusual scalp folds caused by a skin condition were treated with surgery and remained unchanged two years later.

Biotin supplements are unnecessary for most people but may help with certain conditions like biotin deficiency, brittle nails, and some hair loss.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Some skin problems can be signs of diabetes or other metabolic diseases and recognizing them can help diagnose and treat these diseases early.

Cardiovascular drugs can cause various skin problems, so recognizing these reactions is important.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

The document concludes that changes in eyelashes and eyelid skin can indicate various local and systemic diseases.

Changes in the SREBF1 gene cause a rare genetic skin and hair disorder.

New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.

Adapalene 0.1% effectively reduces acne by decreasing comedones and altering skin properties.

SCD1 is crucial for skin health and overall energy balance.