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Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Human hair shows promise for non-invasive medical testing, but more research is needed to standardize its use.

The document concludes that women with PCOS need a comprehensive care model that covers reproductive, metabolic, and psychological health to improve their quality of life.

Healthcare providers need better education and resources to give competent and sensitive care to transgender patients.

Early diagnosis and treatment of PCOS in young people is important to prevent long-term health problems.

Low zinc levels may contribute to hair loss due to increased oxidative DNA damage.

Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

The document concludes that gender-affirming treatments are essential for transgender individuals and outlines safe hormone therapy practices.

A method was found to accurately measure spironolactone and canrenone in blood samples using liquid chromatography-mass spectrometry.

Non-invasive methods show promise for diagnosing skin diseases like psoriasis and lupus but need more research for regular use.

Teriflunomide is an effective and generally safe oral treatment for relapsing MS, reducing relapses and slowing disability progression.

Healthcare providers need better education and policies to serve transgender individuals effectively.

People with Alopecia Areata are more likely to have prediabetes and obesity.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

The case emphasizes the need for careful screening in children for insulin resistance and related conditions.

A Korean woman with complete hair loss regrew her hair after taking tofacitinib, with no side effects.

The article concludes that better diagnosis and management of Polycystic Ovarian Syndrome are needed to improve women's health and prevent related diseases.

JAK-inhibitors for alopecia areata are generally safe with mostly mild side effects and a low rate of treatment withdrawal.

New imaging techniques can assess and track changes in mouse acne without harm, aiding treatment choices.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

New findings suggest certain genes and microRNAs are crucial for wound healing, and innovative technologies like smart bandages and apps show promise in improving treatment.

The method reliably profiles eicosanoids and shows epitestosterone reduces their levels, similar to common anti-inflammatory drugs.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Adequate vitamin D might lower, and high hair chromium might increase DNA damage in obese women.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.