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The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

Gastric exclusion surgery caused major weight loss and health improvements but led to some anemia and vitamin deficiencies.

UV-B light increases inflammation-related substances in acne-related skin cells.

Southeast Asian herbs show promise for skin and hair care, but more research is needed to confirm their effectiveness in cosmetics.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

ILK is essential for skin development, pigmentation, and healing.

A man with multiple autoimmune diseases developed liver injury from azathioprine, but his liver improved after stopping the drug.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

Researchers found 617 genes that behave differently in cashmere goat hair follicles, which could help understand hair growth.

Pharmacists should interpret lab data and perform physical exams to improve patient care.

Prolonged linseed ingestion is safe for rabbits.

Adding soybean oil to Nonomuraea dietziae increases production of a beneficial compound by improving metabolism and enzyme systems.

Tridax procumbens has medicinal properties like healing, pain relief, and infection control.

Isotretinoin is a preferred treatment for severe acne, often leading to long-term improvement, but requires careful monitoring due to potential side effects.

Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.

Vitamin D is important for skin health and can help treat and prevent various skin conditions.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

Ziziphus spina-christi leaf extract lowered blood sugar and protected organs in diabetic rats.

The patient with autoimmune hypothyroidism improved after treatment for thyroid and associated conditions.

Scarred skin in lichen planopilaris loses immune cells due to a decrease in a specific protein in skin cells.

Dutasteride improved hair density and thickness in men not helped by finasteride, with minimal side effects.

The method reliably profiles eicosanoids and shows epitestosterone reduces their levels, similar to common anti-inflammatory drugs.

Some plant-based treatments may help with ovary function, insulin resistance, and excess male hormones in PCOS, but more research is needed to confirm their safety and effectiveness.

Androgens and other hormones affect hair growth and skin conditions like acne.