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Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

Light can turn on hair growth cells through a nerve path starting in the eyes.

The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

Zinc can both inhibit and stimulate mouse hair growth, and might help recover hair after chemotherapy.

Applying a specific inhibitor lightens skin and hair color.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Prostaglandin D₂ might be targeted for new male pattern baldness treatments.

Improving the environment and cell interactions is key for creating human hair in the lab.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

Some women with acne have higher levels of free testosterone, which might suggest using hormonal treatments for acne.

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.