32 citations
,
January 2015 in “Indian Dermatology Online Journal” This study found that a combination of topical minoxidil and finasteride helped maintain hair density in patients with androgenetic alopecia after initial oral finasteride treatment.
14 citations
,
October 2016 in “Psychoneuroendocrinology” This study identified significant changes in the expression of nine proteins in the nucleus accumbens of rats treated with finasteride, suggesting potential novel targets for its neuropsychiatric effects.
9 citations
,
July 2020 in “Experimental Dermatology” This review emphasizes the potential of repurposing topical L-thyroxine for skin ulcers and telogen effluvium and highlights the need for further exploration of its use in dermatology.
5 citations
,
November 2020 in “JAMA Dermatology” Finasteride may cause side effects; more research needed.
June 2025 in “International Journal of Research and Review” This review concluded that Unani medicine offers a promising holistic approach to managing androgenetic alopecia by focusing on humoral balance and follicular rejuvenation, but further scientific validation is needed for widespread clinical use.
September 2021 in “International journal of Ayurveda and pharma research” In this case report, a patient with subclinical hypothyroidism exhibited a significant reduction in TSH levels after four months of ayurvedic treatment, but levels slightly increased afterward.
81 citations
,
May 2007 in “Fertility and Sterility” This review discusses the safety of testosterone therapy for postmenopausal women and concludes that, aside from hirsutism and acne, it appears safe at physiological doses for several years, though more long-term studies are needed.
77 citations
,
May 2012 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are effective and should be personalized.
43 citations
,
January 2016 in “International Journal of Andrology” This study found that men experiencing long-term symptoms after finasteride use for androgenetic alopecia frequently reported loss of penis sensitivity and anhedonia, among other effects, indicating potential post-finasteride syndrome.
35 citations
,
May 2012 in “Cochrane Database of Systematic Reviews” This review found evidence supporting the effectiveness and safety of topical minoxidil for treating female pattern hair loss, though many included studies were at high risk of bias.
31 citations
,
January 1995 in “The American journal of medicine” This article reviews the role of 5α-reductase in cutaneous hyperandrogenism and the potential of 5α-reductase inhibitors and antiandrogens in treating conditions like hirsutism and male-pattern baldness, reporting no clinical results.
30 citations
,
April 1997 in “European journal of endocrinology” The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.
21 citations
,
May 2016 in “The Cochrane library” This review found that while topical minoxidil is effective for treating female pattern hair loss, finasteride showed no more effectiveness than placebo, and low-level laser therapy increased hair count but with inconsistent results.
20 citations
,
September 2019 in “Epidemiology and Psychiatric Sciences” This review discusses post-SSRI sexual dysfunction syndrome and highlights its significant clinical and regulatory implications, but reports no new findings.
14 citations
,
August 2018 in “Journal of Pharmaceutical and Biomedical Analysis” This study found that finasteride maintained chemical and physical stability in various excipient mixtures, which may guide the development of stable topical delivery systems.
11 citations
,
October 2015 in “Dermatology and therapy” This study found that finasteride use for androgenetic alopecia was not associated with increased sexual dysfunction compared to an age-matched control group.
8 citations
,
July 2018 in “Current Sexual Health Reports” This review discusses post-finasteride syndrome, emphasizing its serious psychological and cognitive symptoms and the need for more research and awareness in the medical community, but provides no new clinical findings.
8 citations
,
April 2014 in “Practical Diabetes” This article discusses the significant impact of shame on diabetes self-management and emphasizes the need to address it in therapy, although it presents no new clinical results.
5 citations
,
March 2019 in “Facial Plastic Surgery Clinics of North America” In this article, the authors reviewed essential terminology and recommendations for creating a welcoming healthcare environment for transgender patients and providing gender-affirming therapy, emphasizing the unique health needs and disparities faced by this population.
4 citations
,
January 2018 in “Elsevier eBooks” This chapter discusses the sources, classifications, and effects of hormones, their role in disease treatment and food security, and reports no new results.
3 citations
,
September 2014 in “Journal of obstetrics and gynaecology Canada” Menopause often leads to lower sexual desire and discomfort during sex, but treatment should be personalized and only if it bothers the woman.
1 citations
,
November 2015 in “Cochrane library” This protocol outlines a planned Cochrane Review to evaluate the effects of 5-alpha-reductase inhibitors on lower urinary tract symptoms caused by benign prostatic obstruction, and it reports no new findings.
1 citations
,
July 2011 in “Climacteric” Long-term estrogen therapy in postmenopausal women can improve certain health markers, hair loss is common regardless of hormone use, stopping estrogen doesn't increase breast cancer risk, smoking does, and a balanced BMI is linked to lower mortality.
1 citations
,
April 2009 in “Cochrane Database of Systematic Reviews” This protocol outlines a planned Cochrane Review assessing the effectiveness and safety of treatments for androgenic alopecia in women, reporting no new research findings.
1 citations
,
January 2009 in “Cochrane Database of Systematic Reviews” This protocol outlines a planned Cochrane Review to evaluate the effectiveness and safety of treatment options for androgenic alopecia in women, without reporting new findings yet.
April 2024 in “International journal of impotence research” Some men experience persistent sexual, neurological, and psychological symptoms after stopping finasteride, but evidence of permanent damage is inconclusive.
November 2023 in “Research Square (Research Square)” This animal study found that finasteride, a 5-alpha reductase type 2 inhibitor, decreased dihydrotestosterone levels and c-Fos protein activation in the rat brain, but these effects may diminish after discontinuing the drug.
September 2023 in “Kerala Journal of Ayurveda” In this case report, a 24-year-old woman with PCOS-related symptoms improved her menstrual regularity and reduced symptoms like mood swings and facial hair growth through Ayurvedic treatments, highlighting their potential role in managing secondary amenorrhea without adverse effects.
September 2016 in “Princeton University Press eBooks” The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.
97 citations
,
November 1986 in “Journal of Steroid Biochemistry” This review discusses the pharmacological properties and clinical applications of cyproterone acetate and similar antiandrogens, noting previous failures in local applications due to concentration limitations; it reports no new empirical results.