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Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

New treatments for male hypogonadism are effective and should be personalized.

High levels of male hormones and irregular periods best predict how well PCOS patients will respond to metformin treatment.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Metformin improved menstrual cycle regularity and signs of hyperandrogenism in adolescent girls with type 1 diabetes but did not improve blood sugar control.

High doses of finasteride cause cell growth and tumors in mice.

Finasteride causes abnormal growth in male mice cells at high doses.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

SHBG binding properties are unchanged in male liver cirrhosis patients.

PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.

The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Metformin helps reduce PCOS-related infertility by improving insulin sensitivity and inducing ovulation.

PCOS in lean women is a serious health condition with implications beyond fertility, affecting metabolism and increasing cardiovascular disease risk.

PCOS is a hormonal disorder causing symptoms like irregular periods and acne, and increases the risk of diabetes and heart disease.

The document concludes that early diagnosis and treatment of PCOS in teenagers is important for managing symptoms and preventing long-term health problems.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Finasteride effectively treats male hair loss, improving growth and density.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.