1 citations
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September 2022 in “Problems of Endocrinology” This review discusses sex differences in Parkinson's disease and highlights that while men are more frequently affected, androgen-modulating treatments have not yet proven effective for PD, though 5α-reductase inhibitors show potential for further study.
1 citations
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January 2006 This article reviews the pathophysiology and causes of androgen-mediated hair growth in hirsutism but does not report any clinical outcomes; treatment aspects are discussed separately.
April 2026 in “International Journal of Impotence Research” This review outlines the major health consequences of anabolic-androgenic steroid abuse, with a focus on sexual and reproductive issues, and suggests management prioritizes cessation and relapse prevention due to lack of robust randomized trials.
January 2026 in “Archive ouverte UNIGE (University of Geneva)” This narrative review examined skin-sparing techniques in gynecomastia surgery and found satisfactory thoracic remodeling with acceptable morbidity and reduced scarring, but acknowledged methodological differences that limit decisive conclusions.
January 2025 in “Open Life Sciences” This study observed that transgenic mice with overexpression of HE4 developed keratitis and severe corneal opacity, suggesting that HE4 may significantly influence keratopathy and inflammatory responses in the eye.
December 2023 in “Frontiers in endocrinology” This review explores the role of hyperandrogenism, including adrenal-derived 11-oxygenated androgen, in the development of polycystic ovarian syndrome and discusses potential therapeutic strategies targeting androgen excess, without reporting new clinical results.
October 2023 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This review found that hyperandrogenism in premenopausal women is linked to a higher prevalence of cardiovascular risk factors and diseases regardless of obesity, while in postmenopausal women, these risks depend on obesity.
October 2023 in “Frontiers in endocrinology” This review investigates molecular mechanisms behind PCOS pathogenesis and discusses potential therapies, but reports no new clinical results.
September 2022 in “Curēus” This case report describes a 61-year-old female with hyperandrogenic symptoms, where an ovarian hemangioma with stromal luteinization was identified and surgically removed, resulting in improved symptoms.
September 2021 in “Physiology News” This abstract appears to consist entirely of repeated color specifications and logo guidelines, providing no research findings or new results.
September 2021 in “Physiology News” This abstract contains only graphic design specifications and reports no new research findings.
This research focused on formulating finasteride, dutasteride, and minoxidil with cyclodextrins to enhance their solubility and skin penetration for topical use, potentially reducing scalp irritation from current alcohol-based preparations.
January 2020 in “Journal of South Asian Federation of Obstetrics and Gynaecology” In this case study, laparoscopic bilateral salpingo-oophorectomy was associated with reduced androgen levels and partial reversal of male-pattern hair loss in a postmenopausal woman with ovarian hyperandrogenism.
August 2019 in “Journal of archaeological science: Reports/Journal of archaeological science: reports” This study demonstrated that cortisol, estradiol, and testosterone are preserved in archaeological human hair, allowing for the analysis of ancient stress and reproductive hormone patterns.
Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.
January 2014 in “Side effects of drugs annual” This review discusses the 2011 publications on the side effects of sex hormones and related compounds, without reporting new clinical results.
January 2010 in “Yearbook of Endocrinology” Older men with lower levels of available testosterone are more likely to be frail.
January 2023 in “Pediatric Endocrinology Diabetes and Metabolism” This review discusses current knowledge of isolated premature pubarche in infants and reports no new findings, highlighting it as a mild, self-limiting condition that necessitates exclusion of serious causes.
June 2021 in “Archives of Advances in Biosciences” This study suggests that finasteride at doses of 5 mg/kg BW or higher may adversely affect spermatogenesis and male fertility in NMRI mice.
March 2000 in “The Journal of pharmacy technology” This review discusses the use of finasteride for treating androgenetic alopecia in men, noting its effectiveness in maintaining and regrowing hair on the scalp and top of the head.
658 citations
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June 2003 in “Endocrine reviews” This review discusses the role of androgens in the progression of cardiovascular disease and explores novel therapeutic targets without reporting new clinical results.
253 citations
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March 2006 in “The Journal of Clinical Endocrinology and Metabolism” This review discusses the hypothesis that polycystic ovary syndrome may originate in fetal life due to prenatal androgen exposure, but reports no new clinical results.
228 citations
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January 2021 in “Journal of Neuroimmune Pharmacology” This review explores possible reasons for why male COVID-19 patients experience more severe symptoms and higher fatality rates than female patients but provides no new clinical results.
82 citations
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January 2000 in “Hormone Research in Paediatrics” This study describes the enzymatic processes through which DHEA is converted to active sex steroids in human skin, highlighting an androgenic effect on sebaceous glands and estrogenic effects in the vagina.
52 citations
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February 2006 in “Current pharmaceutical design” This review discusses the use of 5α-reductase inhibitors in treating benign prostatic hyperplasia, highlighting their long-term effectiveness and benefits when combined with α1-adrenergic antagonists; it reports no new clinical results.
47 citations
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September 2016 in “Reviews in endocrine and metabolic disorders” This review discusses the steroidogenic properties of human skin and suggests that impaired steroidogenesis may be linked to conditions like acne, rosacea, atopic dermatitis, and androgenic alopecia, but reports no new clinical results.
40 citations
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September 2019 in “Molecular and Cellular Endocrinology” This paper discusses mechanisms by which various chemicals disrupt male sexual differentiation, concluding that mixture risk assessments should include a broader set of compounds beyond phthalates to address cumulative reproductive health risks.
38 citations
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December 2009 in “Therapeutic Advances in Medical Oncology” This discussion proposes a model to incorporate patients with hormone-resistant prostate cancer into the existing framework by redefining hormone resistance and exploring new therapeutic approaches.
31 citations
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January 2014 in “Journal of endocrinological investigation” This study reviewed Woodhouse-Sakati syndrome and found it consistently associated with hypogonadism, decreased IGF1, and frontotemporal alopecia, with additional symptoms like intellectual disabilities and diabetes in some patients.
28 citations
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July 2017 in “Journal of Endocrinological Investigation” This study suggests that early onset androgenetic alopecia in men may indicate a male PCOS equivalent, possibly leading to higher risks of metabolic and cardiovascular disorders later in life.