179 citations,
May 1982 in “The Journal of clinical investigation/The journal of clinical investigation” High levels of 3 alpha-diol glucuronide in the blood are a marker of increased androgen action in women with excessive hair growth of unknown cause.
88 citations,
September 2003 in “Clinical endocrinology” Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.
68 citations,
January 2022 in “International Journal of Molecular Sciences” PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.
59 citations,
August 2004 in “Human Reproduction Update” Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.
46 citations,
January 2020 in “Research” Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.
43 citations,
July 2003 in “Andrology” Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.
39 citations,
September 2015 in “Clinical Therapeutics” Teriflunomide effectively reduces relapse rates and disease progression in multiple sclerosis but is not safe for use during pregnancy.
20 citations,
December 1994 in “Fertility and sterility” Flutamide combined with a low-dose birth control pill effectively reduces excessive hair growth in women with polycystic ovarian disease.
18 citations,
June 2019 in “Clinical research in dermatology” Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.
9 citations,
June 2020 in “Trials” The trial aims to test if spironolactone is an effective acne treatment for women without the side effects of current treatments.
7 citations,
August 2023 in “EClinicalMedicine” Anti-androgens can help manage some PCOS symptoms better than metformin but are not more effective than placebos or birth control pills for other symptoms.
6 citations,
October 1998 in “Journal of endocrinological investigation” Antiandrogens help manage PCOS symptoms but need careful monitoring.
6 citations,
February 2021 in “Frontiers in Neurology” Cyclosporine-A can cause serious blood clots in the brain, so patients need careful monitoring.
4 citations,
August 2023 in “Materials” New synthetic polymers help improve skin wound healing and can be enhanced by adding natural materials and medicines.
4 citations,
December 2022 in “Frontiers in Endocrinology” Treating non-classic congenital adrenal hyperplasia is complex because the benefits of hormone treatment must be weighed against potential health risks.
2 citations,
December 2022 in “Journal of Clinical Medicine” Medications for glucose metabolism and weight control, combined therapy options, and herbal medicines may help regulate menstrual cycle in adolescents with PCOS.
1 citations,
January 2024 in “Journal of personalized medicine” Hormonal imbalances during menopause may significantly contribute to Frontal Fibrosing Alopecia.
1 citations,
July 2023 in “Pharmaceutics” New microneedles deliver drugs through the skin accurately and effectively.
1 citations,
June 2022 in “JAAD case reports” A woman developed a severe skin reaction after getting a birth control implant.
1 citations,
August 2021 in “Arhivʺ vnutrennej mediciny” Hormonal imbalances can cause hair loss, and understanding them can help develop better treatments.
1 citations,
February 2017 in “Journal of gynecology and womens health” The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.
Certain drugs can worsen hair loss in people prone to androgenetic alopecia.
August 2024 in “Medicine” Most patients with PCOS were prescribed medroxyprogesterone acetate or oral contraceptives, with some experiencing side effects or needing prescription changes.
March 2024 in “Journal of pharmacy & pharmaceutical sciences” Polymeric microneedles offer a less invasive, long-lasting drug delivery method that improves patient compliance and reduces side effects.
February 2024 in “Endocrinology and Disorders” Balanced hormones are crucial for women's health, and can be managed with lifestyle changes or hormone therapy if needed.
September 2022 in “Dermato” Adult acne is often related to hormonal disorders, especially in women, and may need long-term treatment involving specialists.
July 2011 in “Journal of Pediatric and Adolescent Gynecology” A 15-year-old girl has a skin condition causing blisters on her feet, likely inherited from her family.
January 2008 in “The European Journal of Contraception & Reproductive Health Care” Non-daily contraceptives cause fewer side effects and are more satisfying to women, and certain oral contraceptives can treat acne and seborrhoea, with a combination of chlormadinone acetate and ethinyl estradiol being highly effective and safe.
1514 citations,
December 2011 in “Fertility and sterility” Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.
12 citations,
August 2017 in “Pharmaceutical medicine” Most doctors know the thrombosis risk with Cyproterone/Ethinylestradiol, but some lack details on less common risks and patient instructions; educational materials are underused but useful.