July 2025 in “Human Genomics” This source reports that a comprehensive review of LSS gene variant phenotypes enhances understanding of congenital hypotrichosis 14 and could guide more precise genetic counseling and future research into disease mechanisms and potential therapies.
This study investigated the potential mechanisms of Curcuma aeruginosa in treating androgenetic alopecia and identified 66 bioactive compounds interacting with proteins involved in the disorder, suggesting its involvement in hormone response and specific signaling pathways.
May 2023 in “Scientific Reports” This study found that Lepidium sativum seed extract showed potential in treating alopecia in rats by reducing 5(alpha)-dihydrotestosterone levels and improving hair length compared to minoxidil.
This study identified seven new compounds from the plant Sansevieria trifasciata Prain and predicted that four of them may have better anti-alopecia activity than minoxidil through an in silico approach.
13 citations
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October 1960 in “Experimental Biology and Medicine” This study found that small amounts of subcutaneously injected Se75 were deposited and retained in the hair of dogs for up to 316 days.
November 2006 in “評価・診断に関するシンポジウム講演論文集” This study found that KSR1 is essential for v-Ha-ras-mediated skin tumor formation in mice but not for MT-driven mammary tumor genesis, suggesting its potential as a therapeutic target in Ras/MAPK signaling.
5 citations
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January 1976 Under the conditions of this research, Leucaena was generally unpalatable for heifers, caused health issues like goitre and hair loss, and did not significantly increase fertility or productivity.
2 citations
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July 2016 in “Veterinary dermatology” This study reports that hyperaesthetic leucotrichia primarily affects Arabian and American paint horses, occurring mainly in summer, with histological differences from erythema multiforme despite some shared features.
July 2024 in “Journal of Investigative Dermatology” ATR12-351 ointment safely delivers LEKTI protein to the skin, reducing enzyme activity in Netherton syndrome.
2 citations
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April 2008 in “PubMed” This study identified the c.1204G to A (p.E402K) mutation in the hHB6 gene as a cause of monilethrix in a Chinese family, highlighting the gene's role in the condition.
April 2024 in “Anais Brasileiros de Dermatologia”
3 citations
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September 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that enhanced wound healing in oral mucosa involves a SOX2-regulated transcriptional network which includes increased expression of keratin K75, and interaction of K75 with the LINC complex may play a crucial role in promoting rapid wound repair.
19 citations
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September 1995 in “Food and nutrition bulletin” This article reviews the toxic effects of mimosine in Leucaena leucocephala and discusses various methods to mitigate its toxicity but presents no new findings.
35 citations
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August 1978 in “Australian Veterinary Journal” In this study, a sole diet of Leucaena leucocephala caused hypothyroidism and poor weight gain in steers, but mineral supplementation improved some symptoms without normalizing thyroid hormone levels.
June 2020 in “Jurnal Penyakit Dalam Indonesia” This case study highlights that primary biliary cholangitis in a patient with systemic lupus erythematosus can respond well to ursodeoxycholic acid therapy, and anti-DFS70 findings may require further evaluation for other nonsystemic autoimmune conditions.
14 citations
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January 2020 in “Korean Journal of Family Medicine” This case study reported a rare occurrence of lepromatous leprosy with Lucio phenomenon in a 50-year-old Indonesian living in Malaysia, highlighting the necessity for primary care practitioners, even in non-endemic areas, to recognize this serious leprosy reaction to prevent complications and transmission.
4 citations
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March 2017 in “Al-Mi’galaẗ al-sa'udiyaẗ lī-ulum al-ḥayaẗ” In this study, Leonuri Herba alkaloids significantly reduced prostate hyperplasia indicators and improved urinary parameters in hormone-induced model rats.
5 citations
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March 2020 in “Thoracic Cancer” In this phase I study, CT-707, a new ALK inhibitor, showed a 77% response rate among Chinese patients with advanced ALK-rearranged non-small cell lung cancer, suggesting clinical effectiveness despite some adverse events like diarrhea and liver enzyme elevation.
1 citations
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October 2010 in “2010 3rd International Conference on Biomedical Engineering and Informatics” This study successfully cloned and characterized the LEF-1 gene from Inner Mongolia Cashmere Goats, potentially aiding efforts to enhance cashmere production through genetic modification.
September 2022 in “Frontiers in genetics” This case study reports a new LAMB3 mutation linked to junctional epidermolysis bullosa with severe urinary tract stenosis, outlining treatment challenges and expanding knowledge of EB-related urological complications.
18 citations
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January 2015 in “Experimental Dermatology” This study reports new monilethrix cases in Venezuela, the Netherlands, Belgium, and France, expanding the known mutational spectrum of the disorder with novel mutations in KRT81, KRT83, and KRT86 genes.
November 2022 in “Journal of Investigative Dermatology” This study identified 15 Iranian patients with PLEC variants linked to various plectinopathies and highlighted a novel association between a homozygous nonsense variant in PLEC and a rare combination of disorders including EB pruriginosa, muscular dystrophy, and congenital myasthenic syndrome.
3 citations
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January 2011 in “生物医学研究杂志:英文版” In this study, a novel heterozygous transition mutation in the KRT86 gene was identified, which may be pathogenic for monilethrix in a Chinese family.
December 2019 in “University of Malaya Students Repository” This study found that Soxhlet extraction is more effective at removing the toxin mimosine from Leucaena leucocephala, and mimosine shows promise as a biodiesel additive due to its antioxidative properties.
November 2023 in “TẠP CHÍ KHOA HỌC TRƯỜNG ĐẠI HỌC QUỐC TẾ HỒNG BÀNG” This study isolated and identified three natural compounds—syringaresinol, mayuenolid, and ciwujiaton—from Leersia hexandra, a traditional liver treatment used in Huyện Tam Nông, Đồng Tháp, using advanced chromatography and spectroscopy techniques.
May 2013 in “Proceedings of SPIE” In this study, the researchers demonstrated an automatic alignment method for beams in an electron pumped excimer laser system that achieved high precision and accuracy, with a reported alignment accuracy of 0.63μrad.
3 citations
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February 2011 in “Journal of Biomedical Research/Journal of biomedical research” This study identified a novel mutation, R430Q in the KRT86 gene, in a Han family with monilethrix, which may contribute to the disease's pathogenic mechanism.
10 citations
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January 2020 in “Journal of Materials Chemistry B” This study developed a biodegradable nanofibrous biofilm that attracts skin-related cells and accelerates blood vessel formation, potentially improving skin wound healing.
January 2026 in “China CDC Weekly” This study explored using large language models to automatically identify monkeypox cases from electronic medical records, finding that models based on DeepSeek features performed better than traditional methods, with logistic regression showing high accuracy in detecting key symptoms like fever and rash.
37 citations
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June 2000 in “Experimental dermatology” This study investigated a spontaneous mutation in mice resulting in hair abnormalities and elevated IgE levels, which resembles human Netherton's syndrome and monilethrix.