research Antiandrogenic Therapy With Finasteride Attenuates Cardiac Hypertrophy and Left Ventricular Dysfunction
Finasteride helps reduce heart issues and improves heart function.
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research Systematic Review and Meta-Analysis of the Efficacy and Safety of Leflunomide and Methotrexate in the Treatment of Rheumatoid Arthritis
Leflunomide and methotrexate are equally effective for rheumatoid arthritis but have different side effects.
research Lymphoid Enhancer-Binding Factor-1 Interacts with the DNA-Binding Domain of the Vitamin D Receptor
LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.
research Leflunomide for the Treatment of Trichodysplasia Spinulosa in a Liver Transplant Recipient
Leflunomide successfully treated a rare skin condition in a liver transplant patient.
research Maternal Androgen Excess Induces Cardiac Hypertrophy and Left Ventricular Dysfunction in Female Mice Offspring
High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.
research Alopecia Universalis During Treatment with Leflunomide and Adalimumab: Case Report
A patient lost all their hair while on rheumatoid arthritis medication.
research Left Ventricular Function in Patients with Polycystic Ovary Syndrome: A Doppler Echocardiographic Study
Young women with PCOS without additional risk factors may have normal heart function.
research Recalcitrant Alopecia Areata Responsive to Leflunomide and Anthralin—Potentially Undiscovered JAK/STAT Inhibitors?
Leflunomide and anthralin may effectively treat severe alopecia areata.
research Systematic Review and Meta-Analysis of the Efficacy and Safety of Leflunomide and Methotrexate in the Treatment of Rheumatoid Arthritis
Leflunomide and methotrexate are similarly effective for rheumatoid arthritis but have different side effects.
research Impaired LEF1 Activation Accelerates iPSC-Derived Keratinocytes Differentiation in Hutchinson-Gilford Progeria Syndrome
Faulty LEF1 activation causes faster skin cell differentiation in premature aging syndrome.
research Leflunomide: An Unlikely Trigger and Mechanistically a Beneficial Drug for Alopecia Areata
Leflunomide is more likely to help treat alopecia areata than cause it.
research Dermal Fibroblast Expression of LEF1 Is Critical to Normal Skin and Hair Development and Regenerative Wound Healing in Mice
Lef1 is essential for normal skin, hair growth, and healing wounds in mice.
research Left Anterior Descending Coronary Artery Fistula to Main Pulmonary Artery with Triple Vessel Disease: A Report of Two Cases
Two patients with heart issues had successful surgeries and improved symptoms.
research Lef1 Expression in Fibroblasts Maintains Developmental Potential in Adult Skin to Regenerate Wounds
Lef1 helps adult skin cells maintain their ability to heal wounds and regenerate hair, but the study's methods and conclusions have been questioned.
research Left Ventricular Myocardial Mass Index and Its Correlates as an Early Marker of Cardiovascular Risk Among Nonobese Normotensive Indian Women With Polycystic Ovary Syndrome: Lessons From a Cross-Sectional Study
Nonobese, normotensive Indian women with PCOS may have a higher risk of heart problems linked to inflammation and insulin resistance.
research Leflunomide
Leflunomide is effective for rheumatoid arthritis but has significant side effects.
research Dermal Papilla Cell-Derived Exosomes Regulate Hair Follicle Stem Cell Proliferation via LEF1
Exosomes from skin cells can boost hair growth by stimulating a gene called LEF1.
research Papillon-Lefèvre Syndrome: A Rare Case Report of Two Brothers and Review of the Literature
Papillon-Lefèvre Syndrome causes early tooth loss and skin issues, needing early dental diagnosis.
research Papillon-Lefèvre Syndrome: A Rare Case Report and a Brief Review of Literature
Early detection and multidisciplinary treatment are crucial for managing Papillon-Lefévre syndrome.
research Minoxidil in Patients with Chronic Left Heart Failure: Contrasting Hemodynamic and Clinical Effects in a Controlled Trial
Minoxidil helps heart function but doesn't improve exercise ability and may cause complications.
research Effects of Captopril and Minoxidil on Left Ventricular Hypertrophy in Resistant Hypertensive Patients: A 6-Month Double-Blind Comparison
Captopril reduces heart mass, while minoxidil has opposite effects and side effects.
research Finasteride Effectively Attenuates the Impairments of Left Ventricular Function and Cardiac Sympathovagal Balance in Both Aging and Obese Male Rats via Reducing Systemic Oxidative Stress
Finasteride improves heart function and balance in aging and obese male rats by reducing oxidative stress.
research Postmenopausal Virilization Due to a Rare Left Ovarian Androgen-Secreting Leydig Cell Tumor Identified by Ovarian Vein Sampling
A woman's masculine symptoms were caused by a rare tumor in her left ovary, which was found using a special blood test.
research Near Missed Diagnosis of Merkel Cell Carcinoma in a Young Immunocompetent Woman With a Recurrent Left-Arm Mass: A Case Report
A young woman with a rare skin cancer was diagnosed late because her symptoms were unusual for the disease.
research Non-Invasive Quick Diagnosis of Cardiovascular Problems from Visible and Invisible Abnormal Changes with Increased Cardiac Troponin I Appearing on Cardiovascular Representation Areas of the Eyebrows, Left Upper Lip, etc. of the Face and Hands: Beneficial Manual Stimulation of Hands for Acute Anginal Chest Pain, and Important Factors in Safe, Effective Treatment
Visible and invisible changes on the face and hands can indicate heart problems, and manual hand stimulation can relieve chest pain.
research Mechanisms of Submucosal Gland Morphogenesis in the Airway
LEF1 is essential for the development of airway glands and is regulated by the Wnt/ß-catenin pathway.
research Clinical Significance of Intravesical Prostatic Protrusion/Prostate Volume
The IPP index is linked to storage symptoms and leftover urine, and may help manage urinary tract symptoms.
research Correction of the High Female Hairline
The hairline-lowering surgery was effective, safe, and left patients satisfied with few complications.
research Oleoma: Rare Complication of Mesotherapy for Cellulite
A woman got a rare condition called oleoma after cellulite treatment, which left scars even after treatment.
research Erosive Pustular Dermatosis of the Scalp from Topical Minoxidil 5% Solution
A woman developed a scalp condition from using minoxidil, which improved with a different treatment but left scarring.