Recalcitrant Alopecia Areata Responsive to Leflunomide and Anthralin—Potentially Undiscovered JAK/STAT Inhibitors?

    October 2018 in “ Pediatric dermatology ”
    Kabir Sardana, Aastha Gupta, R. K. Gautam
    Image of study
    TLDR Leflunomide and anthralin may effectively treat severe alopecia areata.
    The document discussed a case of a child with severe ophiasis-pattern alopecia areata (AA) that was unresponsive to steroid therapy. The child was successfully treated with a combination of leflunomide and anthralin, which might have worked through the inhibition of the JAK/STAT pathway. This case suggested that this combination could be a cost-effective alternative to more expensive JAK inhibitors for treating recalcitrant AA.
    Discuss this study in the Community →

    Research cited in this study

    7 / 7 results

    Related Community Posts Join

    6 / 1000+ results

      community Alopecia Areata Question

      in Treatment  2 upvotes 3 years ago
      A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

      community mbp alopecia areata or vitamin deficiency

      in Chat 5 months ago
      A 19-year-old male has been using topical finasteride and minoxidil for 8 months with no progress and is considering seeking a second opinion due to potential misdiagnosis. The discussion revolves around whether the hair loss is due to male pattern baldness, alopecia areata, or a vitamin deficiency.

      community Olumiant alternative for Alopecia Areata?

      in Treatment  1 upvotes 1 year ago
      A user with alopecia areata is considering treatment options like injections or Olumiant but is concerned about cost and whether delaying treatment will lead to permanent hair loss. They are seeking alternative treatments that are more affordable for a college student.

    Related Research

    1 / 1 results