22 citations
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March 2017 in “Transplant Infectious Disease” This case report describes successful treatment of generalized trichodysplasia spinulosa with leflunomide in a patient undergoing immunosuppressive therapy following solid organ transplantation.
16 citations
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April 2014 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This report describes a case of universal alopecia in a patient with rheumatoid arthritis while using adalimumab and leflunomide, suggesting a potential link between these drugs and alopecia areata.
11 citations
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October 2018 in “Pediatric dermatology” In this case report, the authors describe a child with treatment-resistant alopecia areata who successfully responded to leflunomide and anthralin, proposing this combination as a potentially cost-effective alternative for managing recalcitrant cases by possibly inhibiting the JAK/STAT pathway.
6 citations
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December 2015 in “Medwave” This article presents a case of alopecia universalis linked to leflunomide use and reviews its application in rheumatoid arthritis treatment, highlighting potential adverse effects.
2 citations
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January 2023 in “SAGE Open Medical Case Reports” In this case report, discontinuing leflunomide resolved chronic cutaneous ulcers in a 67-year-old woman, suggesting a potential link between long-term leflunomide use and ulcer formation.