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medication that treats rheumatoid arthritis by inhibiting immune cell proliferation

Leflunomide is a medication primarily used to treat rheumatoid arthritis by reducing inflammation and slowing down the immune system's attack on the joints. It works by inhibiting an enzyme called dihydroorotate dehydrogenase, which is crucial for the synthesis of pyrimidine, a building block of DNA and RNA, thereby limiting the proliferation of rapidly dividing cells, such as those involved in the immune response.