research Symposium 6-4: Recent Progress in the Treatment of Male Pattern Hair Loss: Lasers and Devices
Laser and light treatments show promise for hair growth but need more research.
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research At-Home Laser and Light-Based Devices
At-home laser and light devices can safely reduce acne and hair growth when used correctly but are less effective than professional treatments.
research Advanced Skin Antisepsis: Application of UVA-Cleavable Hydroxyethyl Starch Nanocapsules for Improved Eradication of Hair Follicle-Associated Microorganisms
New UVA-responsive nanocapsules effectively kill microorganisms in hair follicles when activated by light.
research Platelet-Rich Plasma Therapy with Excellent Results in the Treatment of Post-Infectious Telogen Effluvium
Platelet-Rich Plasma therapy helped significantly in hair recovery for a hair loss condition after infection.
research Efficacy Comparison of Photobiomodulation Devices in the Treatment of Androgenetic Alopecia
In-person laser treatments help hair growth in androgenetic alopecia.
research Antizyme Release Is an Early Event in Ornithine Decarboxylase Induction by Hair Plucking
Hair plucking in rats led to a rapid decrease in ornithine decarboxylase (ODC) activity, while other skin enzymes remained unaffected. The study suggested the presence of an inhibitor, known as antizyme, which was released early during the induction of ODC by hair plucking. Treatment with 10% (NH4)2SO4 increased ODC activity by approximately 75% in enzyme preparations, indicating that antizyme levels increased in plucked skin extracts after such treatment.
research Nonsurgical Cosmetic Practice and COVID-19
The COVID-19 pandemic has caused a 57% increase in interest in facial cosmetic procedures, leading to calls for better industry regulation and professional standards.
research An Overview on Herbal Shampoo Formulation and Development
Herbal shampoos clean and improve hair naturally without harmful side effects.
research Surgical Approaches for Repigmenting Vitiligo 2.0
Assessing CD8+ T cell levels before surgery may improve vitiligo treatment outcomes.
research Follicular Unit: The Center for Hair Transplants
New hair transplant methods now look more natural.
research Evidence That Myc Activation Depletes the Epidermal Stem Cell Compartment by Modulating Adhesive Interactions with the Local Microenvironment
The study demonstrated that Myc activation in mouse epidermis led to the depletion of the epidermal stem cell compartment by altering adhesive interactions with the local microenvironment. This was evidenced by the transcriptional analysis of over 10,000 genes, revealing that Myc activation induced genes related to RNA and protein synthesis, cell proliferation, and differentiation, while downregulating over 40% of genes associated with cell adhesion and cytoskeleton proteins. These changes impaired keratinocyte adhesion, motility, and wound healing, correlating with decreased expression of extracellular matrix proteins and integrins, and reduced formation of hemidesmosomes and actomyosin cytoskeleton assembly. Consequently, Myc activation prompted stem cell exit and differentiation into sebocytes and interfollicular epidermis at the expense of hair lineages, due to impaired keratinocyte migration necessary for hair differentiation.
research Age-Associated Inflammation Connects RAS-Induced Senescence to Stem Cell Dysfunction and Epidermal Malignancy
Older skin has higher cancer risk due to inflammation and stem cell issues.
research Maternal Western Diet Causes Inflammatory Milk and TLR2/4-Dependent Neonatal Toxicity
A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.
research Adult Epidermal Notch Activity Induces Dermal Accumulation of T Cells and Neural Crest Derivatives Through Upregulation of Jagged 1
Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
research Loss of Msx2 Function Down-Regulates the FoxE3 Expression and Results in Anterior Segment Dysgenesis Resembling Peters Anomaly
Loss of Msx2 function causes eye development issues similar to Peters anomaly.
research Acute Sensitivity of the Oral Mucosa to Oncogenic K-ras
Oncogenic K-ras causes rapid cancerous changes in the mouth's lining.
research WWOX Deficiency Causes Downregulation of Prosurvival ERK Signaling and Abnormal Homeostatic Responses in Mouse Skin
WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.
research Impact of the COVID-19 Surge on Phototherapy in Taiwan: Experience From a University Hospital
The COVID-19 pandemic caused a drop in phototherapy for skin conditions, with only 40% of vitiligo and psoriasis patients returning after a hospital closure in Taiwan.
research Stromal-Vascular Fraction of Adipose Tissue: Prospects for Regenerative Bioengineering
Fat tissue's stromal-vascular fraction has stem cells that could be used for regenerative medicine, but official treatment protocols are not yet approved.
research Gut Inflammation Induced by Finasteride Withdrawal: Therapeutic Effect of Allopregnanolone in Adult Male Rats
Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.
research Conditional Telomerase Induction Causes Proliferation of Hair Follicle Stem Cells
Activating TERT in mice skin boosts hair growth by waking up hair follicle stem cells.
research Overexpression of Activin A in the Skin of Transgenic Mice Reveals New Activities in Epidermal Morphogenesis, Dermal Fibrosis, and Wound Repair
Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.
research Lack of the Vitamin D Receptor Is Associated with Reduced Epidermal Differentiation and Hair Follicle Growth
Vitamin D Receptor is crucial for normal skin and hair growth.
research Overexpression of Smad7 Results in Severe Pathological Alterations in Multiple Epithelial Tissues
Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.
research Activation of Nrf2 in Keratinocytes Causes Chloracne-Like Skin Disease in Mice
Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.
research Defects in Mitochondrial DNA Replication and Oxidative Damage in Muscle of mtDNA Mutator Mice
Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.
research Overexpression of Aldo-Keto Reductase 1C3 in LNCaP Cells Diverts Androgen Metabolism Towards Testosterone Resulting in Resistance to the 5α-Reductase Inhibitor Finasteride
Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.
research Coactivator MED1 Ablation in Keratinocytes Results in Hair-Cycling Defects and Epidermal Alterations
Deleting MED1 in skin cells causes hair loss and skin changes.
research Loss of Keratin 10 Is Accompanied by Increased Sebocyte Proliferation and Differentiation
Without keratin 10, there's more growth and development of oil-producing skin cells.
research Cellular and Metabolic Basis for the Ichthyotic Phenotype in NIPAL4 (Ichthyin)–Deficient Canines
Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.