Stromal-Vascular Fraction of Adipose Tissue: Prospects for Regenerative Bioengineering

The rapid development of plastic aesthetic surgery has led to increased research into the properties of adipose tissue left after liposuction operations. This has helped to describe its potential and reveal that the stromal-vascular fraction (SVF) of adipose tissue contains stem cells, which could be a potential source of materials for regenerative medicine. Currently, dozens of studies are being conducted to explore the potential of SVF, including its application in skin problems, scars, osteoarthritis, tendinopathy, wound healing, androgenetic alopecia, vasculopathy, migraines, and vocal cord scarring. Despite the significant number of studies and potential prospects, there are still no officially approved protocols and permissions for using this technique to treat specific diseases, as there are not enough experiments conducted and the legal regulation of this area is not yet formed. This work analyzes the latest systematic and concise literature reviews regarding the biological properties, clinical applications, and regulatory requirements of SVF with the aim of forming a general idea about the current status of SVF of adipose tissue as an alternative source for regenerative medicine.