8 citations
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September 2016 in “Asian journal of beauty & cosmetology” In this study, the methanol-ultrasound extract of Dendropanax morbifera leaf showed potential for use in functional cosmetics and hair growth products due to its high antioxidant capacity and effects on growth factor expression without cytotoxicity.
April 2026 in “Dove Medical Press (Taylor and Francis Group)” This study found that Myrtus communis leaf extract significantly decreased IL-1α and increased VEGF gene expressions in human keratinocytes, which may relate to the plant's traditional uses for hair loss and wound healing, though further research is needed to explore these effects.
April 2026 in “SHILAP Revista de lepidopterología” In this study, Myrtus communis leaf extract significantly reduced IL-1α expression and increased VEGF expression in human keratinocytes, which the researchers suggest may be linked to its traditional use in treating hair loss and wound healing. Further investigation is needed to clarify its mechanisms.
April 2026 in “Clinical Cosmetic and Investigational Dermatology” In this study, exposure to Myrtus communis leaf extract significantly reduced IL-1α expression and increased VEGF expression in human keratinocytes, which may relate to its traditional use for hair loss and wound healing; further research is necessary to understand its mechanisms.
In this animal study, leaf extracts of Kalanchoe pinnata increased hair length in rabbits in a concentration-related manner, surpassing minoxidil at the highest concentration, though hair mass was unaffected.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers developed and tested an eco-friendly herbal hair gel containing extracts from curry leaf, flaxseed, and Aloe vera, finding that formulation F9 excelled in viscosity, spreadability, extrudability, antifungal activity, and stability, making it a promising sustainable alternative to synthetic hair gels.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study formulated and tested eco-friendly herbal hair gels using extracts from curry leaf, flaxseed, and Aloe vera, finding that formulation F9 showed optimal viscosity, spreadability, superior antifungal activity, and stability over six months, making it a promising sustainable alternative to synthetic hair gels.
June 2026 in “Functional Foods in Health and Disease” This study found that water extract of olive leaf may enhance markers linked to epidermal and dermal stem cell activity and potentially improve skin aging, especially in individuals who do not exercise regularly.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed a natural hair serum using rice and guava leaf extracts, evaluating its composition and properties for improving hair quality, reducing hair fall, and nourishing the scalp, though specific results are not detailed in the abstract.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study focused on developing a phytoextract-based hair serum from rice and guava leaf extracts, designed to improve hair quality and scalp health. The formulations were evaluated for their biochemical properties and stability, emphasizing natural ingredients to address hair care needs.
In this study, human dermal papilla cells exposed to wasabi leaf extract showed changes in cytokine-related gene expression, which the authors suggest could help clarify the biological effects of wasabi.
December 2024 in “Proceeding International Collaborative Conference on Multidisciplinary Science” In this study, researchers developed a shampoo using ambon banana peel and green tea leaves, reporting that it showed positive characteristics and was safe for addressing hair loss, with optimal viscosity levels achieved in certain formulations.
November 2024 in “International Journal of Pharmaceutical Sciences Review and Research” This study evaluated herbal hair gels made with extracts of flax seed and curry leaves, finding that the formulations offered good texture, stability, and sensory appeal while promoting healthy hair and scalp without irritation, making them suitable for regular use.
In this study, the combination of binahong leaf and lemongrass extracts was found to effectively inhibit the growth of the dandruff-causing fungus Pityrosporum ovale, with the strongest fungal growth inhibition observed at a 50% concentration of each extract.
April 2022 in “Molecules” This study identified two potent 5α-reductase inhibitors from Tectona grandis leaves, and suggests that ethanol is a preferable solvent for extracting these compounds, which are potential ingredients for hair loss treatments.
December 2021 in “Ad-Dawaa' Journal of Pharmaceutical Sciences” This study concluded that hair tonic formulations using extracts of green tea leaves, celery leaves, or their combination can effectively promote hair growth in guinea pigs, with the fastest growth seen using a 2.5% green tea to 7.5% celery leaf extract ratio.
20 citations
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February 2018 in “Cell transplantation” This study found that the water extract of Cinnamomum osmophloeum Kanehira leaves enhanced hair growth in vitro and in a mouse model, suggesting potential use for treating hair loss.
16 citations
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April 2017 in “Journal of Cosmetic Dermatology” This study found that fig leaf extract significantly downregulated inflammatory and androgenic gene expression in vitro, suggesting potential topical benefits for certain skin disorders.
7 citations
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December 2022 in “Plants” This study suggests that guava leaf extract may inhibit hair loss by downregulating genes involved in androgen synthesis, potentially offering a natural alternative for treating androgenetic alopecia.
3 citations
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April 2016 in “Food Science and Biotechnology” This study found that Oriental melon leaf extracts promoted hair growth in a mouse model and cultured human hair follicles, suggesting potential use as a treatment for hair loss.
2 citations
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November 2021 in “International Journal of Applied Pharmaceutics” This study found that a phytosome lotion made from Mangkokan leaf extract, using a green solvent and microwave-assisted extraction, demonstrated greater hair growth activity than 2% minoxidil, with the 30% phytosome lotion showing the highest efficacy in increasing hair length, weight, and diameter.
This study observed that applying an aqueous extract of Trichosanthes cucumerina leaves to Wistar rats promoted hair growth comparably to 2% Minoxidil, supporting its traditional use for alopecia.
1 citations
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October 2021 in “Jundishapur Journal of Natural Pharmaceutical Products” This study found that methanolic extract of Ficus carica leaves induced apoptosis and inhibited proliferation in B16F10 melanoma cells, suggesting potential anti-cancer properties for further investigation in melanoma.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers developed an herbal hair serum using extracts from guava leaf, onion peel, and neem leaves, finding it improved scalp health, reduced hair breakage, and enhanced hair texture, suggesting potential as a plant-based alternative for hair care.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that an herbal hair serum containing extracts of guava leaf, onion peel, and neem leaves improved scalp health, reduced hair breakage, and enhanced hair texture, suggesting potential as an effective alternative to synthetic hair products.
January 2026 in “International Journal of Health Engineering and Technology” In this study, researchers evaluated the effects of green spinach leaf extract on hair growth in New Zealand rabbits and found that the 15% concentration formula resulted in the highest average hair growth compared to other concentrations and controls.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study tested the acute toxicity of Ficus platyphylla methanol leaf extract in Wistar rats and found no mortality or significant liver enzyme changes at doses up to 5000 mg/kg, suggesting a high margin of acute safety and supporting its traditional use under short-term exposure.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that the methanol leaf extract of Ficus platyphylla demonstrated a high margin of acute safety in Wistar rats, showing minimal risk under short-term exposure with no mortality at doses up to 5000 mg/kg and no significant changes in liver enzyme activities.
November 2025 in “Journal of English Language and Education” In this study, researchers found that a hair tonic formulated with 2% guava leaf extract demonstrated strong consumer acceptance and safe physicochemical characteristics among university students, showing potential as a natural alternative for reducing hair loss.
November 2025 in “Frontiers in Nutrition” Olive leaf extract may help reduce aging signs in postmenopausal women.