This study found that patients with lichen planopilaris exhibit a higher pro-atherogenic lipid profile and elevated atherogenic indexes, suggesting a need for increased cardiovascular and lipid monitoring in these individuals.
This study found that low-level laser therapy may enhance wound healing and reduce pain, swelling, and inflammation by increasing mitochondrial activity and oxidative stress, leading to greater protein synthesis and cell proliferation.
40 citations
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January 2017 in “Intestinal Research” This study found that among Japanese IBD patients, the NUDT15 p.Arg139Cys variant was significantly associated with thiopurine-induced leukopenia and severe hair loss, suggesting its genotyping is important for predicting these adverse events.
November 2024 in “Journal of Investigative Dermatology” This study identified PTEN as a key regulator in non-healing venous leg ulcers, suppressing immune responses and lymphangiogenesis, suggesting its potential as a therapeutic target for promoting VLU healing.
6 citations
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October 2018 in “Lasers in Medical Science” This article explores the potential of photobiomodulation for coronary health, suggesting protective effects after heart attacks and in inaccessible ischemic heart conditions, but presents no new clinical results.
87 citations
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March 2017 in “Journal of Clinical Investigation” In this study, researchers identified PSENEN mutations that can lead to a form of Dowling-Degos disease, characterized by follicular hyperkeratosis and an increased susceptibility to acne inversa, especially in the presence of certain trigger factors.
June 2020 in “Zenodo (CERN European Organization for Nuclear Research)” This study suggests that the DNMT3B -579 G>T polymorphism may be a genetic risk factor for colorectal cancer in the Azerbaijani population.
18 citations
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May 2011 in “Journal of Investigative Dermatology” Wnt signaling affects the development and growth of Langerhans cells in mice.
1 citations
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January 2021 in “Journal of Cutaneous and Aesthetic Surgery” This review indicates that low-level laser therapy may stimulate hair growth in both men and women with androgenetic alopecia, showing similar efficacy to minoxidil in some studies, but requires more robust evidence.
5 citations
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November 2024 in “Journal of Clinical Immunology” This study reports that a 9-week-old infant with Netherton syndrome showed rapid and sustained symptom improvement, including skin microbiome normalization and developmental progress, after off-label dupilumab treatment, without adverse reactions.
April 2026 in “International Journal of Clinical Case Reports and Reviews” In this preclinical study, researchers developed and evaluated a new non-invasive laser system designed for personalized medical use, showing its potential for chronic disease management and adjunctive fat reduction by offering enhanced treatment precision and adaptability over existing devices.
9 citations
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November 2021 in “PubMed” This study found that FDA-approved low-level light/laser therapy devices significantly increased hair density in individuals with pattern hair loss compared to sham devices.
October 2017 in “Data Archiving and Networked Services (DANS)” This thesis found that in lupus nephritis, traditional classification criteria may not apply to patients with glomerular deposits without clinical SLE, indicating distinct prognostic and diagnostic challenges.
7 citations
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April 2021 in “Journal of Lower Genital Tract Disease” This study concluded that erosive lichen sclerosus is a distinct subtype marked by red patches on hairless skin, while ulcerated lichen sclerosus typically results from trauma in uncontrolled dermatosis.
1 citations
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October 2023 in “Skin research and technology” This study found that line-field confocal optical coherence tomography effectively visualized key diagnostic features of classic lichen planopilaris in real time, suggesting its potential as a valuable diagnostic tool.
4 citations
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April 2024 in “Clinical Cosmetic and Investigational Dermatology” This review examines the trichoscopic characteristics of scalp DLE and LPP, correlating these findings with histopathological data, but provides no new clinical results.
1461 citations
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March 2004 in “Annals of oncology” This study found that in first-line treatment of metastatic breast cancer, pegylated liposomal doxorubicin (PLD) provided similar progression-free survival to doxorubicin with significantly less cardiotoxicity.
10 citations
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June 2018 in “Journal of visualized experiments” This study demonstrated that lactate dehydrogenase activity is notably high in quiescent hair follicle stem cells within mouse skin using a specific enzymatic activity assay.
In this study, researchers found no significant differences in the serum levels of DHEAs, DHT, and testosterone between female patients with oral lichen planus and healthy controls, suggesting no neuroendocrine etiology is associated with this condition.
This thesis found that desmoplakin mutations in cardiocutaneous syndrome are linked to dose-dependent disease severity and identified mechanisms by which KLHL24 mutations cause cardiomyopathy, with rescue experiments successfully preventing this phenotype in patient-derived heart tissues.
In this study, PDLLA treatment in middle-aged mice was observed to enhance hair growth by increasing macrophage M2 polarization and hair follicle stem cell proliferation, potentially rejuvenating the skin's microenvironment and offering a novel approach for age-related hair loss.
1 citations
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April 2016 in “British Journal of Dermatology” Buschke-Ollendorff syndrome is a rare genetic disorder causing skin and bone changes, with some cases also showing ADHD or developmental delays.
16 citations
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February 2005 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that VDR deficiency in mice leads to various skin pathologies but does not affect the phenotype or function of Langerhans cells.
April 2016 in “Journal of Investigative Dermatology” This study reported that the absence of Lsh in skin led to significant epidermal hyperplasia and altered gene expression, suggesting its crucial role in regulating epidermal proliferation, differentiation, and wound healing.
September 2018 in “International Journal of Dermatology” This case report about anterolateral leg alopecia discusses a potentially underreported condition with no new clinical results available.
17 citations
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May 2018 in “Journal of Cosmetic Dermatology” This study reports that nonscarring diffuse hair loss in women is most common in the 21-40 age group, with low serum ferritin, vitamin B12, and vitamin D3 levels contributing to its pathogenesis.
January 2026 in “Romanian Journal of Military Medicine” This study found that both Lactobacillus casei extract and Newcastle disease virus significantly reduced cell viability and induced apoptosis in human colorectal cancer cells, suggesting these agents could complement standard chemotherapy and radiotherapy after further clinical trials.
5 citations
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January 2014 in “International Journal of Trichology” Hair loss on the lower legs is common in middle-aged men, usually harmless, and doesn't need treatment.
3 citations
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December 2023 in “International Journal of Nanomedicine” Repaglinide-loaded liponiosomal hybrids improve blood sugar control and insulin release better than regular Repaglinide.
This case study reports the first known instance of lichen planopilaris being associated with multiple autoimmune syndrome in a woman with hypothyroidism and Crohn's disease.