Erosive Lichen Sclerosus: A Clinicopathologic Subtype

    April 2021 in “ Journal of Lower Genital Tract Disease ”
    Tania Day, Geoffrey Otton, Graeme Dennerstein, Hong Tran, James Scurry
    TLDR Erosive lichen sclerosus is a distinct subtype with specific skin features, and treatment led to complete resolution in half of the cases.
    The study identified erosive lichen sclerosus (LS) as a distinct clinicopathologic subtype, characterized by red patches on hairless skin with eroded epithelium, differing from ulcerated LS, which was associated with trauma. It involved 25 cases, with 10 classified as erosive LS and 15 as ulcerated LS. Erosive LS was noted for its recalcitrant nature and distinct histopathologic features, while ulcerated LS was linked to uncontrolled LS and comorbidities. The study highlighted the need for centralized referral and expert review for accurate diagnosis, as well as the importance of specialized care in treatment outcomes. Limitations included its retrospective design and small sample size, emphasizing the need for further research and improved referral pathways to vulvar clinics.
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