Erosive Lichen Sclerosus: A Clinicopathologic Subtype

    April 2021 in “ Journal of Lower Genital Tract Disease ”
    Tania Day, Geoffrey Otton, Graeme Dennerstein, Hong Tran, James Scurry
    TLDR Erosive lichen sclerosus is a distinct subtype with specific skin features, and treatment led to complete resolution in half of the cases.
    The study aimed to determine if erosive lichen sclerosus (LS) was a distinct clinicopathologic subtype. It involved 24 women with a mean age of 67 years, identifying 10 cases of erosive LS and 15 of ulcerated LS. Erosive LS was characterized by red patches on hairless skin with eroded epithelium overlying hyalinized or fibrotic collagen, while ulcerated LS was often a secondary effect of uncontrolled dermatosis, associated with diabetes and lack of treatment. All cases were treated with topical steroids, and additional treatments were used in some cases. Complete resolution was achieved in 50% of the cases.
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