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Urotensin II increases growth and VEGF production in rat skin cells by turning on the Wnt-β-catenin pathway.

Impaired ABCA5 activity disrupts cholesterol balance in hair follicle cells, affecting hair growth.

Taking 1 mg finasteride for a year reduces dihydrotestosterone levels in men with early hair loss, but doesn't change their metabolic state.

JAK inhibitors show promise for treating skin conditions like eczema, hair loss, and psoriasis.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

Ectodysplasin inhibits Wnt signaling to help form hair follicles.

Wnt signaling is crucial for skin development and hair growth.

New therapies are being developed that target integrin pathways to treat various diseases.

Janus kinase inhibitors show promise in treating alopecia areata but need better topical formulations.

Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.

Quercetin effectively treated and prevented hair loss in mice.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Cutaneous gene therapy could become a viable treatment for skin and hair disorders with improved vector development and gene expression control.

Oxidative stress plays a significant role in alopecia areata, and new treatments may include JAK inhibitors and antioxidants.

Metformin works better for adolescent girls with PCOS who have certain genetic variations.

Type 1 diabetes often occurs with other autoimmune diseases, and personalized treatment based on genetics can improve outcomes.

Higher BMI and lower testosterone are linked to more aggressive prostate cancer.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.

Myasthenia gravis can affect both motor and non-motor systems due to immune system issues.

More high-quality research is needed to recommend flavonoids and saponins for clinical use.

Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.

Women with PCOS have more Bifidobacterium in their gut compared to those without PCOS.

Coffee berry extract may help slow skin aging and prevent hair loss.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Blocking YAP/TAZ could be a new way to treat skin cancer.

Baricitinib helps regrow hair in adults with severe alopecia better than a placebo and is approved for treatment, but long-term effects are still unknown.

Special gels help heal diabetic foot sores and reduce the risk of amputation or death.

New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.

Cronkhite-Canada syndrome may be more treatable and less severe than previously thought.