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390-420 / 1000+ resultsresearch Advances in Microengineered Platforms for Skin Research
This review highlights the potential of microfluidic skin-on-a-chip models in skin research, emphasizing their ability to mimic human skin structure and improve control over cellular and molecular distribution compared to traditional in vitro models.
research Electrochemical Detector for Liquid Chromatography: Determining Minoxidil in Hair-Growth Pharmaceuticals
This study observed that carbon paste electrodes catalyze the electrooxidation of minoxidil more efficiently than other electrode types, with a detection limit of approximately 20 ng mL^-1.
research IMAGING INSIGHTS INTO JC VIRUS-ASSOCIATED PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY IN NEUROPSYCHIATRIC LUPUS: A CASE REPORT
This case report highlights the challenge of distinguishing between neuropsychiatric lupus and rituximab-associated progressive multifocal leukoencephalopathy in systemic lupus erythematosus patients, emphasizing the importance of early recognition and careful management.
research Manifestation of Hyperandrogenism in the Continuous Light Exposure-Induced PCOS Rat Model
Continuous light exposure in rats leads to PCOS-like symptoms and suggests sleep habits might affect the disorder's development.
research Lichen Planopilaris and Low-Level Light Therapy: Four Case Reports and Review of the Literature About Low-Level Light Therapy and Lichenoid Dermatosis
This study reported that four patients with lichen planopilaris showed dramatic improvement, including symptom reduction and hair regrowth, after treatment with low-level light therapy.
research New 4,800W, 810 nm Diode Laser with a Spot Size of 20x15 mm for Permanent Hair Removal: Pilot Clinical Study
This study evaluated a new high-power, 810 nm diode laser for hair removal, finding it to be effective and safe, with a mean hair reduction of 74.4% in one session, and noted it worked efficiently on both large and small areas with minimal side effects.
research Colorimetry provides a rapid objective measurement of de novo hair growth rate in mice
This study found that tristimulus colorimetry is a sensitive and quantitative method for projecting hair growth rates in depilated mice, and it observed that 890 nm LED irradiation promotes hair regrowth.
research Use of confocal microscopy for nanoparticle drug delivery through skin
This review discusses the application of confocal laser scanning microscopy for studying nanoparticle interactions with skin and highlights its potential for broad applications, but reports no new experimental findings.
research Reply to ‘CD123 immunohistochemistry for plasmacytoid dendritic cells is useful in the diagnosis of scarring alopecia’: three PDC-related parameters are useful in differentiating lupus alopecia from LPP
This letter discusses three plasmacytoid dendritic cell-related parameters that may help differentiate lupus alopecia from lichen planopilaris, but it reports no new study results.
research Results in a ‘Flash’: Recognizing Misleading Clinical Photography
This study highlights the prevalence of photographic bias in before-and-after images in dermatology, emphasizing how factors like lighting and camera angles can mislead patients and influence expectations, often leading to dissatisfaction and unrealistic aesthetic standards.
research Severe form of keratitis–ichthyosis–deafness (KID) syndrome associated with septic complications
This report documents a novel alanine to valine substitution in the GJB2 gene in a Japanese girl with severe keratitis–ichthyosis–deafness syndrome, suggesting a potential link to her severe recurrent infections and immunodeficiency.
research Finasteride for Chronic Central Serous Chorioretinopathy
research Vitamin D receptor ablation alters skin architecture and homeostasis of dendritic epidermal T cells
This study found that VDR deficiency in mice leads to various skin pathologies but does not affect the phenotype or function of Langerhans cells.
research 560 The molecular mechanism of PCE-DP, a novel brightening active ingredient
This study observed that PCE-DP may improve skin pigmentation by increasing epidermal turnover and inhibiting melanin uptake and inflammation in human epidermal keratinocytes.
research How Should You Use the Lab to Monitor Patients Taking a Mood Stabilizer
This review discusses the guidelines for using and monitoring mood stabilizers in bipolar disorders, highlighting that only a minority of patients receive guideline-adherent monitoring.
research The 675 nm laser for the treatment of facial acne scars in dark skin type
This study evaluated the effectiveness of a 675 nm laser device on facial acne scars in patients with darker skin types, finding that 67% reported excellent improvement and 33% reported good improvement, with significant enhancements in skin texture and appearance after five treatments.
research DEEP REINFORCEMENT LEARNING FOR SCALABLE CONTROL OF BOOLEAN MODELS IN THE CONTEXT OF CELLULAR REPROGRAMMING
In this study, researchers developed a novel computational framework using deep reinforcement learning to identify strategies for cellular reprogramming in gene regulatory networks, showing its effectiveness in a model of immune response against infection.
research Label-free concurrent 5-modal microscopy (Co5M) resolves unknown spatio-temporal processes in wound healing
This study introduces a five-modal microscopy technique that allows label-free, in vivo observation and quantitative analysis of various wound healing processes.
research Intense Pulsed Light: From the Past to the Future
This review discusses the development of IPL devices, highlights their established cosmetic uses, such as treating vascular and pigmented lesions, and suggests potential expansion into more effective combination therapies.
research Calendar
research Visual imaging of calcium ion distribution in acetone and tape stripping damaged canine epidermis.
This study established an experimental model to visualize calcium ion distribution after skin barrier damage in canine epidermis, observing that calcium gradients changed differently depending on the type of damage and time elapsed.
research Exploring the Potential of DALL-E 2 in Pediatric Dermatology: A Critical Analysis
This study found that DALL-E 2 performed poorly in generating accurate images of most pediatric dermatological conditions, highlighting the need for more domain-specific and inclusive training data.
research NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor
This study found that the E3 ligases NEDD4 and NEDD4L regulate intestinal stem cell priming by degrading the LGR5 receptor, and their loss leads to increased Wnt activation and crypt proliferation, which in turn accelerates intestinal tumor progression in mice.
research Linear alopecia in pediatrics: RCM and dermoscopy reveal diagnostic cues
This study found that RCM combined with dermoscopy can differentiate disease states between alopecia areata, tinea capitis, nevus sebaceous, and linear scleroderma of the scalp by identifying distinct dermal and follicular patterns.
research Recent advances in cellulose nanocrystals-based sensors: A review
This article reviews the properties of cellulose nanocrystals for sustainable development but presents no new experimental results.
research Prospective, Open-Label, Multi-Centre, Randomized Study to Compare the Effectiveness, Safety, and Tolerability of Lulican™ Shampoo Versus Ketoconazole Shampoo in Indian Adult Patients With Mild to Moderate Scalp Seborrheic Dermatitis (LEAD Study)
In this study, patients with mild to moderate scalp seborrheic dermatitis experienced greater improvements in severity scores and quality of life with Lulican™ shampoo compared to Ketoconazole over four weeks, with similar safety profiles but better tolerability and cosmetic acceptability for LulicanTM.
research Effect of decellularisation methods on methacryloyl-substituted placental ECM hydrogels
This research concluded that the novel hydrogel PlacMA, derived from human placenta and curable by visible light, shows promise for cell culture and tissue engineering applications due to its tunable properties.
research 698 Effect of lithocholic acid as a ligand of vitamin D receptor on hair growth in alopecia
This study suggests that lithocholic acid may enhance hair regeneration in alopecia by activating vitamin D receptors in human dermal papilla cells.
research ILDS Newsletter No. 29
The ILDS Newsletter reported on efforts to support albinism patients in Tanzania and dermatological conferences.